Results 91 to 100 of about 1,732,794 (242)
Advanced Science, EarlyView.ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee +3 more
wiley +1 more source
Enterovirus 71 VP1 activates calmodulin-dependent protein kinase II and results in the rearrangement of vimentin in human astrocyte cells. [PDF]
PLoS ONE, 2013 Enterovirus 71 (EV71) is one of the main causative agents of foot, hand and mouth disease. Its infection usually causes severe central nervous system diseases and complications in infected infants and young children. In the present study, we demonstrated
Cong Haolong +8 more
doaj +1 more source
The Poxviral RING Protein p28 Is a Ubiquitin Ligase That Targets Ubiquitin to Viral Replication Factories [PDF]
Journal of Virology, 2005 ABSTRACT The poxviral RING protein p28 is a virulence factor whose molecular function is unknown. Many cellular RING-containing proteins act as ubiquitin ligases (RING-E3s) connecting selected substrate proteins to the ubiquitination machinery.
Nerenberg, Bianca T Hovey +5 more
openaire +4 more sources
Advanced Intelligent Systems, EarlyView.This review highlights recent advances in automated iPSC culture systems integrating robotics, advanced imaging, artificial intelligence, and process control. These technologies improve reproducibility, scalability, and quality in cell expansion, differentiation, and real‐time monitoring, while emerging AI‐enabled and closed‐loop approaches offer new ...
Hyoryong Lee +3 more
wiley +1 more source
Virology Journal, 2005 Background Replication of the vaccinia virus genome occurs in cytoplasmic factory areas and is dependent on the virus-encoded DNA polymerase and at least four additional viral proteins.
Moss Bernard, De Silva Frank S
doaj +1 more source
Animal Research and One Health, EarlyView.Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke +9 more
wiley +1 more source
Annual report of the Inspector of Factories of the State of Connecticut.
, 1887 Vol. for 1889 has title: Report of the Inspector of Factories of the State of Connecticut.Report year irregular.Mode of access: Internet.Continued by: Connecticut. Office of the Inspector of Factories.
Connecticut. Office of the Inspector of Factories.
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Biotechnology and Bioengineering, EarlyView.Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga +2 more
wiley +1 more source
Amoebae, Giant Viruses, and Virophages Make Up a Complex, Multilayered Threesome
Frontiers in Cellular and Infection Microbiology, 2018 Viral infection had not been observed for amoebae, until the Acanthamoeba polyphaga mimivirus (APMV) was discovered in 2003. APMV belongs to the nucleocytoplasmatic large DNA virus (NCLDV) family and infects not only A.
Jan Diesend +3 more
doaj +1 more source
, 1890 Mode of access: Internet.Continued by: Ohio. Dept. of Inspection of Workshops, Factories and Public Buildings. Annual report of the Department of Inspection of Workshops, Factories and Public Buildings, to the General Assembly of the State of Ohio, for ...
Ohio. Dept. of Inspection of Workshops and Factories. +1 more
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