Results 81 to 90 of about 1,732,794 (242)
The organization and dynamics of viral factories
Journal of VirologyViral factories (VFs) are dynamic, virus-induced microcompartments that serve as centralized hubs in the host cell for viral genome replication, transcription, and virion assembly.
Kathryn S. Brittain +4 more
semanticscholar +1 more source
Brazilian Journal of Microbiology, 2018 Rio Negro virophage (RNV) was co-isolated with a strain of mimivirus named sambavirus, from Brazilian Amazon. We report the near complete genome sequence of RNV, the first virophage isolated in Brazil. We also present new microscopical data demonstrating
I. Borges +3 more
semanticscholar +1 more source
Brd4 Is Displaced from HPV Replication Factories as They Expand and Amplify Viral DNA
PLoS Pathogens, 2013 Replication foci are generated by many viruses to concentrate and localize viral DNA synthesis to specific regions of the cell. Expression of the HPV16 E1 and E2 replication proteins in keratinocytes results in nuclear foci that recruit proteins associated with the host DNA damage response.
Nozomi Sakakibara +7 more
openaire +4 more sources
Herbivory‐Induced Stomatal Opening Triggers the Dispersal of an Invasive Insect Herbivore
Advanced Science, EarlyView.The invasive leafminer Phthorimaea absoluta uniquely manipulates plant defenses by inducing stomatal opening in tomato. This response, mediated by the stomatal regulator IQM1, enhances the release of the repellent volatile benzaldehyde. This volatile triggers the dispersal of adult moths, facilitates colonization of new hosts, and leads to rapid ...
Limin Chen +10 more
wiley +1 more source
Stress Beyond Translation: Poxviruses and More
Viruses, 2016 Poxviruses are large double-stranded DNA viruses that form viral factories in the cytoplasm of host cells. These viruses encode their own transcription machinery, but rely on host translation for protein synthesis. Thus, poxviruses have to cope with and,
Jason Liem, Jia Liu
doaj +1 more source
Viruses, 2022 Flaviviruses replicate in membrane factories associated with the endoplasmic reticulum (ER). Significant levels of flavivirus viral protein accumulation contribute to ER stress. As a consequence, the host cell exhibits an Unfolded Protein Response (UPR),
Grégorie Lebeau +7 more
doaj +1 more source
A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control
Advanced Science, EarlyView.Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias +23 more
wiley +1 more source
Advanced Science, EarlyView.Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi +8 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo +9 more
wiley +1 more source
Order-Oriented Learning Factories: Why and How Learning Factories Have to Adapt
, 2022 S.460-465Current developments in personalized manufacturing are bringing the order more and more into the focus of value adding. By using the example of the learning factory advanced industrial engineering aIE it is shown why for learning factories order
Siegert, Jörg +3 more
core +1 more source