Results 221 to 230 of about 319,921 (262)

Role of N-linked glycosylation sites in human ACE2 in SARS-CoV-2 and hCoV-NL63 infection. [PDF]

open access: yesJ Virol
Noettger S   +7 more
europepmc   +1 more source

Histidine protonation and the activation of viral fusion proteins [PDF]

open access: possibleBiochemical Society Transactions, 2008
Many viral fusion proteins only become activated under mildly acidic condition (pH 4.5–6.5) close to the pKa of histidine side-chain protonation. Analysis of the sequences and structures of influenza HA (haemagglutinin) and flaviviral envelope glycoproteins has led to the identification of a number of histidine residues that are not only fully ...
Bostjan Kobe   +7 more
openaire   +4 more sources

Membrane rearrangements in fusion mediated by viral proteins [PDF]

open access: possibleTrends in Microbiology, 1997
Diverse enveloped viruses enter host cells by fusing their envelopes with cell membranes. The mechanisms of merger of lipid bilayers of two membranes mediated by influenza hemagglutinin and other viral fusion proteins apparently involve local lipidic connections that evolve into a bilayer septum in which a pore forms and expands.
L.V. Chernomordik, Grigory B. Melikyan
openaire   +2 more sources
Some of the next articles are maybe not open access.

Related searches:

Inhibition of Measles Viral Fusion Is Enhanced by Targeting Multiple Domains of the Fusion Protein

ACS Nano, 2021
Measles virus (MeV) infection remains a significant public health threat despite ongoing global efforts to increase vaccine coverage. As eradication of MeV stalls, and vulnerable populations expand, effective antivirals against MeV are in high demand.
Ksenia Rybkina   +11 more
openaire   +4 more sources

Properties of a Viral Fusion Protein

1988
The mechanisms by which proteins mediate biological membrane fusion are not clearly understood. We have analyzed acid-induced changes in influenza hemagglutinin (HA), a viral membrane fusion factor, and correlated them with its acid-triggered fusion activity.
Robert W. Doms, Ari Helenius
openaire   +2 more sources

Fusion inhibition: Bioassay of a Type C viral protein

Virology, 1975
Abstract Based on the observation that concentrated RD-114 virus directly induces fusion in a Rous sarcoma virus-transformed human glioma cell line, KC, an RD-114 virus protein was identified which had the property of inhibiting this fusion. The protein was irreversibly denatured by 2-mercaptoethanol, reacted with neutralizing sera to RD-114 virus ...
James Davis   +4 more
openaire   +3 more sources

Peripherin-2:  An Intracellular Analogy to Viral Fusion Proteins

Biochemistry, 2007
The C-terminus of the intracellular retinal rod outer segment disk protein peripherin-2 binds to membranes, adopts a helical conformation, and promotes membrane fusion, which suggests an analogy to the structure and function of viral envelope fusion proteins. Nuclear magnetic resonance (NMR) data and fluorescence data show that a 63-residue polypeptide
R Lapointe   +4 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy