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Targeting the Hendra Virus Fusion Protein Transmembrane Domain to Inhibit Viral Fusion
The FASEB Journal, 2017Hendra Virus is a zoonotic virus in the family Paramyxoviridae. It is an enveloped, negative sense single stranded RNA virus that is highly pathogenic, but currently there is no approved antiviral therapeutic or vaccine. Further elucidation of the mechanisms that underlie viral entry into a cell will assist in presenting additional targets for ...
Chelsea Barrett +2 more
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Trimeric coiled-coils as viral fusion protein mimics
2008α-Helical coiled-coils, a protein structural motif formed by supercoiling of two or more component polypeptide strands, are ubiquitous mediators of biological structure and function. Their characteristic primary heptad repeat, denoted abcdefg, makes these complexes attractive scaffolds for studying self-assembly and molecular recognition.
Travisano, Philip, Kennan, Alan J.
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Peptide models for the membrane destabilizing actions of viral fusion proteins
Biopolymers, 1992AbstractThe fusion of enveloped viruses to target membranes is promoted by certain viral fusion proteins. However, many other proteins and peptides stabilize bilayer membranes and inhibit membrane fusion. We have evaluated some characteristics of the interaction of peptides that are models of segments of measles and influenza fusion proteins with ...
R M, Epand +6 more
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Molecular Membrane Biology, 2004
Recent crystal structures of Flavivirus and Alphavirus fusion proteins (class II) confirm two major principles of protein machineries that mediate the merger of two opposing lipid bilayers. First, the fusion protein can bridge both membranes tethered by two membrane anchors.
David J, Schibli, Winfried, Weissenhorn
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Recent crystal structures of Flavivirus and Alphavirus fusion proteins (class II) confirm two major principles of protein machineries that mediate the merger of two opposing lipid bilayers. First, the fusion protein can bridge both membranes tethered by two membrane anchors.
David J, Schibli, Winfried, Weissenhorn
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Structural comparison of three viral “fusion” proteins
Biochemical Society Transactions, 1991B H, Nicholson, M, Naase
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Viral and Cellular Membrane Fusion Proteins
Annual Review of Physiology, 1990openaire +2 more sources
Soil viral diversity, ecology and climate change
Nature Reviews Microbiology, 2022Janet K Jansson, Ruonan Wu
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SARS-CoV-2 viral load and shedding kinetics
Nature Reviews Microbiology, 2022Olha Puhach +2 more
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Update on infection control practices in cancer hospitals
Ca-A Cancer Journal for Clinicians, 2018Ella Ariza-Heredia, Roy F Chemaly
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