Results 71 to 80 of about 42,015 (175)

Multiplex PCR to Diagnose Gastrointestinal Infections: Key Limitations in Interpretation

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Multiplex polymerase chain reaction (PCR) panels are increasingly used for the evaluation of acute diarrhea, providing rapid and sensitive detection of a broad range of enteric pathogens. However, their widespread adoption has created important interpretive challenges for clinicians.
Giannoula S. Tansarli, Ferric C. Fang
wiley   +1 more source

Combining RNA Interference and RIG-I Activation to Inhibit Hepatitis E Virus Replication

open access: yesViruses
Hepatitis E virus (HEV) poses a significant global health threat, with an estimated 20 million infections occurring annually. Despite being a self-limiting illness, in most cases, HEV infection can lead to severe outcomes, particularly in pregnant women ...
Mathias Ziersch   +6 more
doaj   +1 more source

Importance of viral pathogens in children with acute gastroenteritis in the south of Iran

open access: yesAnnals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVES: Different types of viruses are the leading cause of acute diarrhea among infants and young children worldwide. Epidemiological surveillance of viral agents is critical for the development of effective preventive measures ...
Akram Najafi   +4 more
doaj   +1 more source

Treatment With Ruxolitinib and TAK‐779 Enhances GII.17 Human Norovirus Replication and Enables Serial Passaging in Human Intestinal Enteroids

open access: yesGenes to Cells, Volume 31, Issue 5, September 2026.
We aimed to establish a simple method for GII.17 human norovirus (HuNoV) replication and serial passaging using wild‐type J2 human intestinal enteroids (HIEs). Treatment with ruxolitinib and TAK‐779, which target interferon and chemokine signaling, respectively, enhances viral replication and enables serial passaging of GII.17. ABSTRACT Human norovirus
Eri Hiraishi   +4 more
wiley   +1 more source

Imaging Characteristics of Pylorogastric, Duodenogastric, and True‐Gastrogastric Intussusception in 25 Dogs and One Cat

open access: yesVeterinary Radiology &Ultrasound, Volume 67, Issue 5, September 2026.
ABSTRACT Gastric intussusception in dogs and cats is uncommon, and there are multiple variations described in the literature. The aim of this study was to describe the imaging characteristics of pylorogastric (PG), duodenogastric (DG), and true‐gastrogastric (true‐GG) intussusceptions.
Dylan Burton   +9 more
wiley   +1 more source

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong   +3 more
wiley   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom   +4 more
wiley   +1 more source

GII.17 norovirus re-emerged in the 2020s as a result of dynamic and adaptive evolutionary processes

open access: yesNature Communications
Over the past two years, increased norovirus activity has been reported in multiple countries, accompanied by a rise in genotype GII.17 prevalence. Despite causing large outbreaks in Asia during 2014-2016, GII.17 has not historically been considered a ...
Kentaro Tohma   +14 more
doaj   +1 more source

Viral gastroenteritis in children: modern concepts of epidemiology and prevention

open access: yesЖурнал инфектологии, 2015
More than 60 original articles and reviews were analyzed in order to study the current state of the epidemiology and prevention of acute intestinal infections (AII) of viral etiology in the world. Interest in a problem of viral AII is determined by their 
K. D. Ermolenko   +2 more
doaj   +1 more source

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