Results 91 to 100 of about 40,056 (225)
Early tocilizumab and outcomes in acute necrotizing encephalopathy
Developmental Medicine &Child Neurology, EarlyView.Early tocilizumab and outcome in acute necrotising encephalopathy. Aim To evaluate the timing and safety of tocilizumab in acute necrotizing encephalopathy (ANE). Method This was a multicentre retrospective study evaluating outcomes (modified Rankin Scale [mRS]) in children with ANE treated with tocilizumab. A logistic regression model determined a cut‐
Velda X Han +14 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio +38 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Objective This study aimed to evaluate the feasibility and safety of venetoclax as a cytoreductive strategy during induction therapy in newly diagnosed acute promyelocytic leukemia (APL), and to provide an exploratory description of its early efficacy.
Yu Wang +3 more
wiley +1 more source
Italian Patients Journey for Gene Therapy in Haemophilia A
Haemophilia, EarlyView.ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno +19 more
wiley +1 more source
Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease
International Journal of Dermatology, EarlyView.Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo +2 more
wiley +1 more source
Journal of Clinical Periodontology, EarlyView.ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra +5 more
wiley +1 more source
Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways
Journal of Periodontal Research, EarlyView.This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru +2 more
wiley +1 more source
Anaemia Among Mother–Child Dyads in India: Trends, Drivers, and Future Projections
Maternal &Child Nutrition, EarlyView.ABSTRACT Anaemia among mothers and their children is a widespread public health challenge with profound consequences for individuals and societies. While anaemia has been studied separately in women and children, there remains a literature gap examining anaemia in mother‐child dyads, limiting insights on interventions that may simultaneously address ...
Sarang Pedgaonker +8 more
wiley +1 more source
Medical and Veterinary Entomology, EarlyView.This study confirms the presence of the tick Hyalomma marginatum Koch, 1844, a known vector of the Crimean‐Congo hemorrhagic fever virus at Galicia. Most ticks were encountered on humans and livestock, with numbers rising between 2019 and 2024, especially during spring and in warm‐summer Mediterranean southwest areas of the studied region.
Inês Abreu Ramos +10 more
wiley +1 more source
Sustained Remission of Pediatric Bowel‐Associated Dermatosis‐Arthritis Syndrome With Risankizumab
Pediatric Dermatology, EarlyView.ABSTRACT Bowel‐associated dermatosis‐arthritis syndrome (BADAS) is a rare neutrophilic dermatosis characterized by recurrent fever, arthralgias, and skin eruptions, most commonly occurring in patients with inflammatory bowel disease. We report the case of a 17‐year‐old female with Crohn's disease who developed BADAS and achieved complete and durable ...
Kylie E. Peake +4 more
wiley +1 more source