Results 81 to 90 of about 63,777 (241)
Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)
Bioethics, EarlyView.ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk +4 more
wiley +1 more source
HISTORY OF THE STUDY OF HEMORRHAGIC FEVER ETIOLOGY WITH RENAL SYNDROME
Медицинский совет, 2017 Hemorrhagic fever with renal syndrome (HFRS) is an acute viral disease of zoonotic nature, characterized by systemic lesions of small vessels, hemorrhagic diathesis, hemodynamic disorders and a peculiar renal disease (interstitial nephritis with acute ...
E. A. TKACHENKO, A. A. ISHMUKHAMETOV
doaj +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, EarlyView.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Testicular degeneration and infertility following arbovirus infection [PDF]
, 2018 Arboviruses can cause a variety of clinical signs including febrile illness, arthritis, encephalitis and hemorrhagic fever. The recent Zika epidemic highlighted the possibility that arboviruses may also negatively affect the male reproductive tract.
Dattena, Maria +11 more
core +1 more source
Clinical features and patient management of Lujo hemorrhagic fever.
PLoS Neglected Tropical Diseases, 2014 BackgroundIn 2008 a nosocomial outbreak of five cases of viral hemorrhagic fever due to a novel arenavirus, Lujo virus, occurred in Johannesburg, South Africa.
Nivesh H Sewlall +7 more
doaj +1 more source
Newly recognized mosquito-associated viruses in mainland China, in the last two decades
Virology Journal, 2011 There are four principal arboviruses in mainland China. Two kinds of them are mosquito-borne viruses, namely Japanese encephalitis virus and dengue virus, which lead to Japanese encephalitis, and dengue fever/dengue hemorrhagic fever respectively; the ...
Liang Guodong, Gao Xiaoyan, Liu Hong
doaj +1 more source
Presence and persistence of Ebola or Marburg virus in patients and survivors: A rapid systematic review [PDF]
, 2016 Background: The 2013-15 Ebola outbreak was unprecedented due to sustainedtransmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance ...
Brainard, Julii +4 more
core +3 more sources
Surgical excision of melanomas in the anal region and reconstruction of the anus in 11 horses
Equine Veterinary Education, EarlyView.Summary This case report describes the surgical excision of large perianal and perineal melanomas, and reconstruction of the anus in 11 grey horses. Four horses had a history of painful defaecation or urination due to extensive tumours. Seven horses had no clinical signs at the time of admission but had rapidly growing nodules around the anus with ...
F. Somm, A. E. Fürst, M. A. Jackson
wiley +1 more source
Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone
Emerging Infectious Diseases, 2014 Sierra Leone in West Africa is in a Lassa fever–hyperendemic region that also includes Guinea and Liberia. Each year, suspected Lassa fever cases result in submission of ≈500–700 samples to the Kenema Government Hospital Lassa Diagnostic Laboratory in ...
Randal J. Schoepp +4 more
doaj +1 more source
EBOV-RNA test with RT-PCR in ocular fluids of Ebola survivors can help to safely perform cataract surgery [PDF]
, 2018 Since the Ebola virus (EBOV) was discovered in 1976, the recent 2014−2016 Ebola virus disease (EVD) outbreak in West Africa was the largest with 28,600 cases and about 11,300 deaths.
Iozzo, Nicola, Spadea, Leopoldo
core +1 more source