Results 131 to 140 of about 39,531 (226)
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang +3 more
wiley +1 more source
Assessment of the integrated disease surveillance and response system implementation in health zones at risk for viral hemorrhagic fever outbreaks in North Kivu, Democratic Republic of the Congo, following a major Ebola outbreak, 2021. [PDF]
Kallay R +12 more
europepmc +1 more source
Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade +5 more
wiley +1 more source
High awareness of viral outbreaks in Dar es Salaam coexists with critical knowledge gaps, stigma, and vaccine hesitancy driven by trust and safety concerns. Targeted myth correction, anti‐stigma initiatives, and strategic digital health communication are essential to strengthen community preparedness and outbreak response.
Mohammed Elmogiera Fadlallh Elsayed +2 more
wiley +1 more source
Tick‐Tac‐Foe: When Ticks, Trade, and Zoonotic Pathogens Align in African Wet Meat Markets
ABSTRACT Zoonotic diseases account for over ∼60% of infectious diseases and present a significantly growing fatality threat in Africa. Live and wet markets (LWMs) in Africa function as key economic venues that support human livelihoods through social interaction and trade in food stuff, including meat and other animal‐based products.
Allen Takudzwa Munaro
wiley +1 more source
Infectious Disease Response in Tanzania: Enhanced Strategies From the 2023 to 2025 Marburg Outbreaks
ABSTRACT The 2023 Marburg virus disease (MVD) outbreak in Tanzania, which resulted in nine confirmed cases and six deaths (case fatality rate [CFR]: 66.7%), served as a critical stress test of the national health system, revealing significant gaps in outbreak preparedness across surveillance, laboratory capacity, and infection prevention and control ...
Huda Haque +6 more
wiley +1 more source
Spatial projections revealed high‐risk areas for YF transmission, highlighting priority zones for targeted vaccination efforts in GLTs. By integrating disease ecology into conservation planning, this study offers a scalable framework for spatially informed interventions aimed at mitigating disease‐driven declines in threatened species.
Maxime Pierron +5 more
wiley +1 more source
Abstract Background and aims Tissue‐retained needles from intravenous drug use can cause rare but severe complications, ranging from local to systemic infections to needle embolization. Due to the limited evidence and the lack of epidemiological studies on the issue, we systematically reviewed the literature focusing on case reports and case series on ...
Heidi Laukkala +7 more
wiley +1 more source
Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk +4 more
wiley +1 more source

