Abstract Introduction The development of approaches and interventions to achieve HIV remission continues to accelerate. Children living with HIV who started antiretroviral therapy (ART) at a young age and sustain viral suppression are an ideal clinical trial population. Trials may require analytic treatment interruptions (ATIs).
Holly L. Peay +17 more
wiley +1 more source
mRNA vaccines for HBV: Mechanisms, preclinical advances, and therapeutic clinical progress. [PDF]
Pechnikova NA +6 more
europepmc +1 more source
Construction of Reverse Genetics System for Feline Calicivirus FCV‐BJ616 and Proteomic Analysis
This study successfully isolated the FCV‐BJ616 strain derived from cats and established a reverse genetics system. In vivo experiments showed that rFCV‐BJ616 exhibits wild‐type virulence, leading to high fever, weight loss, and multi‐organ lesions in infected cats. Proteomic analysis indicated that both rFCV‐BJ616 and FCV‐BJ616 share similar regulatory
Chunmei Xu +9 more
wiley +1 more source
The Role of MASP1, MASP2, and Mannose-Binding Lectin in the Immune Response to Hepatitis B Vaccination in Infants. [PDF]
Tapcı AE +9 more
europepmc +1 more source
Response to Comments on 'Hepatitis B Virus (HBV) Treatment Eligibility in the UK: Retrospective Longitudinal Cohort Data to Explore the Impact of Changes in Clinical Guidelines'. [PDF]
Journal of Viral Hepatitis, Volume 33, Issue 2, February 2026.
Campbell C +4 more
europepmc +2 more sources
Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin +12 more
wiley +1 more source
Yeast-Based Vaccine Platforms: Applications and Key Insights from the COVID-19 Era. [PDF]
Baindara P, Dinata R, Kumar R.
europepmc +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
A review of vaccinology and <i>ex vivo</i> antigen-loaded dendritic cells: A different approach to infectious disease vaccines. [PDF]
Dillman RO, Nistor GI, Keirstead HS.
europepmc +1 more source
State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding +6 more
wiley +1 more source

