Results 31 to 40 of about 3,154,220 (254)
Retrovirology, 2016 Regulatory T cells (Tregs) have been shown to limit anti-viral immunity during chronic retroviral infection and to restrict vaccine-induced T cell responses.
T. Knuschke +9 more
semanticscholar +1 more source
Detection of viral infections by innate immunity.
Biochemical Pharmacology, 2020 Pattern recognition receptors (PRRs) and inflammasomes are a key part of the anti-viral innate immune system as they detect conserved viral pathogen-associated molecular patterns (PAMPs).
M. Carty, Coralie Guy, A. Bowie
semanticscholar +1 more source
RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.
Cell Reports, 2016 Plasmacytoid dendritic cells (pDCs) represent a unique immune cell type that responds to viral nucleic acids through the rapid production of type I interferons.
Michael Chopin +10 more
semanticscholar +1 more source
The Interplay Between Viral-Derived miRNAs and Host Immunity During Infection
Frontiers in Immunology, 2020 MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Richa Mishra +3 more
semanticscholar +1 more source
Viral and Cellular MicroRNAs as Determinants of Viral Pathogenesis and Immunity [PDF]
Cell Host & Microbe, 2008 MicroRNAs (miRNAs) have recently emerged as key posttranscriptional regulators of gene expression in multicellular eukaryotes. It is increasingly clear that miRNAs of both viral and cellular origin can positively or negatively influence viral replication.
Gottwein, Eva, Cullen, Bryan R.
openaire +2 more sources
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
PLoS Pathogens, 2016 Clinical and experimental studies have shown that estradiol (E2) confers protection against HIV and other sexually transmitted infections. Here, we investigated the underlying mechanism. Better protection in E2-treated mice, immunized against genital HSV-
Varun C. Anipindi +18 more
semanticscholar +1 more source
Viral evolution and Immune responses [PDF]
Journal of Clinical Microbiology and Biochemical Technology, 2019 Antiviral responses are activated rapidly after viral infection in order to control and prevent dissemination of the virus. Different pathways are activated in the immune system, including innate and adaptive responses. On the other hand, viruses have evolved specifi c strategies to evade these responses.
openaire +2 more sources
Epidemiology and Immune Pathogenesis of Viral Sepsis [PDF]
Frontiers in Immunology, 2018 Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis can be caused by a broad range of pathogens; however, bacterial infections represent the majority of sepsis cases. Up to 42% of sepsis presentations are culture negative, suggesting a non-bacterial cause.
Gu-Lung Lin +8 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source