Results 11 to 20 of about 3,154,220 (254)
The Challenge of Viral Immunity [PDF]
Immunity, 2007 Bringing together discussion of innate immunity, B cell and T cell responses, vaccine design and efficacy, and the genetics of HIV and AIDS resistance allows us to access the extraordinary complexity of viral immunity and host responsiveness.
Doherty, PC, Turner, SJ
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Viral pseudoenzymes in infection and immunity [PDF]
The FEBS Journal, 2020 Pseudoenzymes are proteins that are evolutionarily related to active enzymes, but lack relevant catalytic activity. As obligate intracellular pathogens, viruses complete their life cycle fully dependent on the cellular supplies of macromolecule and energy.
Ting‐Yu Wang +4 more
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Immunity, 2020 The enzyme cyclic GMP-AMP synthase (cGAS) senses cytosolic DNA in infected and malignant cells and catalyzes the formation of 2'3'cGMP-AMP (cGAMP), which in turn triggers interferon (IFN) production via the STING pathway.
Chun Zhou +28 more
semanticscholar +1 more source
Viral hepatitis prevention by immunization [PDF]
Jornal de Pediatria, 2006 To present an updated review and criticism of viral hepatitis A and B prevention by immunization.Review of medical articles obtained from the MEDLINE database. The most recent and representative articles on the subject (2000-2006) were selected. The Centers for Disease Control and Prevention (CDC), American Academy of Pediatrics (AAP), Brazilian ...
Ferreira, Cristina Helena Targa +1 more
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Viral mechanisms of immune evasion [PDF]
Immunology Today, 2000 During the millions of years they have coexisted with their hosts, viruses have learned how to manipulate host immune control mechanisms. Viral gene functions provide an overview of many relevant principles in cell biology and immunology. Our knowledge of viral gene functions must be integrated into virus-host interaction networks to understand viral ...
Alcami, Antonio, Koszinowski, Ulrich H.
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Characterization of anti-viral immunity in recovered individuals infected by SARS-CoV-2
medRxiv, 2020 The WHO has declared SARS-CoV-2 outbreak a public health emergency of international concern. However, to date, there was hardly any study in characterizing the immune responses, especially adaptive immune responses to SARS-CoV-2 infection. In this study,
Chen Dong +16 more
semanticscholar +1 more source
Translating viral vaccines into immunity
Science, 2021 How adenoviral vaccines orchestrate adaptive immunity from innate responses is ...
Juno, Jennifer A., OConnor, Shelby L.
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TLR2-mediated innate immune priming boosts lung anti-viral immunity
European Respiratory Journal, 2020 Background We assessed whether Toll-like receptor (TLR)2 activation boosts the innate immune response to rhinovirus infection, as a treatment strategy for virus-induced respiratory diseases. Methods We employed treatment with a novel TLR2 agonist (INNA-X)
J. Girkin +13 more
semanticscholar +1 more source
Sex Differences in Immunity to Viral Infections
Frontiers in Immunology, 2021 The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following SARS-CoV-2 infection. Strong evidence of a male bias in COVID-19 disease severity is hypothesized to be mediated by sex differential ...
H. Jacobsen, S. Klein
semanticscholar +1 more source