Results 111 to 120 of about 5,389,784 (354)
Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy [PDF]
, 2018 Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection.
Alicino C. +9 more
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Heparanase, cell signaling, and viral infections
Cellular and Molecular Life Sciences, 2020 Heparanase (HPSE) is a multifunctional protein endowed with many non-enzymatic functions and a unique enzymatic activity as an endo-β-d-glucuronidase.
Raghuram Koganti +2 more
semanticscholar +1 more source
PLoS Medicine, 2006 The authors describe recent progress and obstacles to harnessing RNA interference to prevent or treat viral infection.
Dykxhoorn, Derek M., Lieberman, Judy
openaire +5 more sources
Frontiers in Immunology, 2019 The importance of the cellular immune response against DENV has been increasingly highlighted in the past few years, in particular for vaccine development.
Paolla B. A. Pinto +8 more
doaj +1 more source
Frontiers in Immunology, 2020 Viral vectors are increasingly used as delivery means to induce a specific immunity in humans and animals. However, they also impact the immune system, and it depends on the given context whether this is beneficial or not.
Adrien Leite Pereira +9 more
doaj +1 more source
Viral infections of oral cavity
Journal of Family Medicine and Primary Care, 2020 Viral infections of the oral cavity usually manifest as either ulceration or blistering presentation of oral tissues. Oral viral infections are encountered in dental practice but received less clinical interest due to the lesser frequency of patients and
A. Santosh, Keerthi Muddana
semanticscholar +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Immune Checkpoints in Viral Infections
Viruses, 2020 As evidence has mounted that virus-infected cells, such as cancer cells, negatively regulate the function of T-cells via immune checkpoints, it has become increasingly clear that viral infections similarly exploit immune checkpoints as an immune system ...
Huiming Cai +11 more
semanticscholar +1 more source
Immunosuppression in Viral Infections [PDF]
Clinical Infectious Diseases, 1986 Viruses may cause immunosuppression by a variety of mechanisms. This review delineates four categories. First, immunosuppression can result from the direct effects of viral replication on lymphocyte functions. Either all classes of lymphocytes can be affected, as occurs in measles, or the effect can be restricted to a cell subtype, as is the case with ...
B T, Rouse, D W, Horohov
openaire +2 more sources