Results 1 to 10 of about 3,662,996 (361)

The relationship between COVID‐19 viral load and disease severity: A systematic review

Immunity, Inflammation and Disease, 2022
Introduction Patients with COVID‐19 may present different viral loads levels. However, the relationship between viral load and disease severity in COVID‐19 is still unknown.
Omid Dadras, Amir M. Afsahi, Zahra Pashaei, Hengameh Mojdeganlou, Amirali Karimi, Pedram Habibi, Alireza Barzegary, Amirata Fakhfouri, Pegah Mirzapour, Nazanin Janfaza, Soheil Dehghani, Fatemeh Afroughi, Mohsen Dashti, Sepideh Khodaei, Esmaeil Mehraeen, Fabricio Voltarelli, Jean‐Marc Sabatier, SeyedAhmad SeyedAlinaghi   +17 more
doaj   +2 more sources

Modelling upper respiratory viral load dynamics of SARS-CoV-2

BMC Medicine, 2022
Relationships between viral load, severity of illness, and transmissibility of virus are fundamental to understanding pathogenesis and devising better therapeutic and prevention strategies for COVID-19. Here we present within-host modelling of viral load
Joseph D. Challenger, Cher Y. Foo, Yue Wu, Ada W. C. Yan, Mahdi Moradi Marjaneh, Felicity Liew, Ryan S. Thwaites, Lucy C. Okell, Aubrey J. Cunnington   +8 more
doaj   +2 more sources

Temporal dynamics in viral shedding and transmissibility of COVID-19

Nature Medicine, 2020
Eric Ho-Yin Lau, Peng Wu, Jessica Y Wong
exaly   +2 more sources

Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load

bioRxiv, 2023
Immunotherapeutic cytokines can activate immune cells against cancers and chronic infections. N-803 is an IL-15 superagonist that expands CD8+ T cells and increases their cytotoxicity.
J. Cody, Amy L. Ellis-Connell, Shelby L. O’Connor, E. Pienaar   +3 more
semanticscholar   +1 more source

SARS-CoV-2 viral load and shedding kinetics

Nature Reviews Microbiology, 2022
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two key parameters for estimating infectiousness. As shedding of infectious virus is required for onward transmission, understanding shedding characteristics is ...
O. Puhach, B. Meyer, I. Eckerle
semanticscholar   +1 more source

Community viral load – an optimal alternative index of population viral load for HIV/AIDS surveillance

Zhongguo gonggong weisheng, 2022
ObjectiveTo explore an optimal alternative index of population viral load (PVL) suitable for assessing potential human immunodeficiency virus (HIV) transmission in the population of Yining city, Xinjiang Uygur Autonomous Region.
Qian HE, Aizimaiti·Aikebaier, Xiao-min HU   +2 more
doaj   +1 more source

Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Coronavirus disease 2019 (COVID-19) continues to spread rapidly worldwide. Neutralizing antibodies are a potential treatment for COVID-19.
R. Gottlieb, A. Nirula, Peter Chen, J. Boscia, B. Heller, J. Morris, G. Huhn, Jose Cardona, Bharat Mocherla, Valentina Stosor, Imad Shawa, Princy N. Kumar, A. Adams, Jacob Van Naarden, Kenneth L Custer, M. Durante, G. Oakley, A. Schade, T. Holzer, P. Ebert, R. Higgs, N. Kallewaard, J. Sabo, D. Patel, P. Klekotka, Lei-Bin Shen, D. Skovronsky   +26 more
semanticscholar   +1 more source

SARS-CoV-2 Viral Load Is Correlated With the Disease Severity and Mortality in Patients With Cancer

Frontiers in Oncology, 2021
The correlation between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) viral load and risk of disease severity in cancer patients is poorly understood.
Maha Al-Mozaini, Abu Shadat M. Noman, Jawaher Alotaibi, Mohammed Rezaul Karim, A. S. M. Zahed, A. T. M. Rezaul Karim, Khaldoun Alromiah, Syed S. Islam, Syed S. Islam   +8 more
doaj   +1 more source

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients

medRxiv, 2020
Background: Although the SARS-CoV-2 viral load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2 nucleic acid (RNAaemia) could be detected in a fraction of ...
Xiaohua Chen, Binghong Zhao, Y. Qu, Yurou Chen, J. Xiong, Yong Feng, Dong Men, Qianchuan Huang, Y. Liu, Bo Yang, Jinya Ding, Feng Li   +11 more
semanticscholar   +2 more sources

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

New England Journal of Medicine, 2020
SARS-CoV-2 Viral Load in Upper Respiratory Specimens The authors report results of an analysis of nasal and throat swabs from 17 patients in Zhuhai, China, who had received a diagnosis of Covid-19....
L. Zou, Feng Ruan, Mingxing Huang, L. Liang, Huitao Huang, Z. Hong, Jianxiang Yu, Min Kang, Yingchao Song, J. Xia, Qianfang Guo, T. Song, Jianfeng He, H. Yen, M. Peiris, Jie Wu   +15 more
semanticscholar   +1 more source