Results 1 to 10 of about 463,872 (305)

High heritability is compatible with the broad distribution of set point viral load in HIV carriers. [PDF]

PLoS Pathogens, 2015
Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors ...
Sebastian Bonhoeffer, Christophe Fraser, Gabriel E Leventhal   +2 more
doaj   +5 more sources

SARS-CoV-2 Viral Load in Stool and Nasopharyngeal/Oropharyngeal Samples: Implications for Clinical Progression in Severe COVID-19 Patients [PDF]

International Journal of Microbiology
The SARS-CoV-2 RNA load in different specimens has been analyzed to evaluate its correlation with disease outcomes and other factors. However, conflicting results have emerged due to variations in study design.
Mariane Vedovatti Monfardini, Brena Ramos Athaydes, Priscila Marinho Abreu, Fernanda Laís Lima Fonseca, Roberta Ferreira Ventura Mendes, Juliana Couto-Vieira, Frederico Firme Figueira, Priscilla Aquino Martins, Regina Keller, Sandra Lucia Ventorin von Zeidler, Liliana Cruz Spano   +10 more
doaj   +2 more sources

HPV16/HPV58 viral load is non-linearly correlated with cervical lesions and can be used as a triage marker [PDF]

Infectious Agents and Cancer
The significance of viral load from high-risk human papillomavirus (HR-HPV) in the detection of cervical lesions is still debated. This study aims to assess the correlation between the viral load of the most common high-risk genotypes (HPV16, HPV18 ...
Jie Zhou, Bingbing Ma, Jinjin Ji, Jianhong Liao, Hongyan Xu, Hongbo Hu   +5 more
doaj   +2 more sources

Impact of Vaccination and Prior Infection on SARS-CoV-2 Viral Load in Preschool Children During the Omicron Pandemic [PDF]

Vaccines (Basel)
Suzuki M, Tokita A, Inaba M, Tada Y, Shuri K, Miura A, Fukazawa M, Fujioka M, Sakai-Tagawa Y, Yamayoshi S, Iwatsuki-Horimoto K, Kawaoka Y, Miyazawa M.   +12 more
europepmc   +2 more sources

Community viral load – an optimal alternative index of population viral load for HIV/AIDS surveillance

Zhongguo gonggong weisheng, 2022
ObjectiveTo explore an optimal alternative index of population viral load (PVL) suitable for assessing potential human immunodeficiency virus (HIV) transmission in the population of Yining city, Xinjiang Uygur Autonomous Region.
Qian HE, Aizimaiti·Aikebaier, Xiao-min HU   +2 more
doaj   +1 more source

SARS-CoV-2 Viral Load Is Correlated With the Disease Severity and Mortality in Patients With Cancer

Frontiers in Oncology, 2021
The correlation between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) viral load and risk of disease severity in cancer patients is poorly understood.
Maha Al-Mozaini, Abu Shadat M. Noman, Jawaher Alotaibi, Mohammed Rezaul Karim, A. S. M. Zahed, A. T. M. Rezaul Karim, Khaldoun Alromiah, Syed S. Islam, Syed S. Islam   +8 more
doaj   +1 more source

How Can Viral Dynamics Models Inform Endpoint Measures in Clinical Trials of Therapies for Acute Viral Infections? [PDF]

, 2016
Acute viral infections pose many practical challenges for the accurate assessment of the impact of novel therapies on viral growth and decay. Using the example of influenza A, we illustrate how the measurement of infection-related quantities that ...
Anderson, RM, Cauët, E, Cori, A, De Wolf, F, Hadjichrysanthou, C, Lawrence, E, Vegvari, C   +6 more
core   +11 more sources

Research progress on anti-viral treatment for chronic hepatitis B patients with high viral load [PDF]

Xin yixue, 2022
Chronic hepatitis B （CHB） is a severe disease that affects human health. Replication of hepatitis B virus （HBV） is the main cause of morbidity in CHB patients.
Peng Wan, Cao Hong
doaj   +1 more source

Hopes, joys and fears: Meaning and perceptions of viral load testing and low-level viraemia among people on antiretroviral therapy in Uganda: A qualitative study.

PLOS Global Public Health, 2023
Uganda applies the World Health Organization threshold of 1,000 copies/ml to determine HIV viral non-suppression. While there is an emerging concern of low-level viraemia (≥50 to
Nicholus Nanyeenya, Godfrey Siu, Noah Kiwanuka, Fredrick Makumbi, Esther Nasuuna, Damalie Nakanjako, Gertrude Nakigozi, Susan Nabadda, Charles Kiyaga, Simon P S Kibira   +9 more
doaj   +1 more source

Modelling upper respiratory viral load dynamics of SARS-CoV-2

BMC Medicine, 2022
Relationships between viral load, severity of illness, and transmissibility of virus are fundamental to understanding pathogenesis and devising better therapeutic and prevention strategies for COVID-19. Here we present within-host modelling of viral load
Joseph D. Challenger, Cher Y. Foo, Yue Wu, Ada W. C. Yan, Mahdi Moradi Marjaneh, Felicity Liew, Ryan S. Thwaites, Lucy C. Okell, Aubrey J. Cunnington   +8 more
doaj   +1 more source