Results 91 to 100 of about 3,717,929 (382)
Natural selection favoring more transmissible HIV detected in United States molecular transmission network. [PDF]
, 2019 HIV molecular epidemiology can identify clusters of individuals with elevated rates of HIV transmission. These variable transmission rates are primarily driven by host risk behavior; however, the effect of viral traits on variable transmission rates is ...
Campbell, Ellsworth +8 more
core
World Journal of Critical Care Medicine, 2021 BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is diagnosed via real time reverse transcriptase polymerase chain reaction (RT-PCR) and reported as a binary assessment of the test being positive or negative.
Santosh Shenoy
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Disease associated with equine coronavirus infection and high case fatality rate. [PDF]
, 2014 BackgroundEquine coronavirus (ECoV) is associated with clinical disease in adult horses. Outbreaks are associated with a low case fatality rate and a small number of animals with signs of encephalopathic disease are described.ObjectivesThe aim of this ...
Fielding, CL +7 more
core +1 more source
Evaluation of HIV viral load turnaround time in Moshi, Tanzania
Journal of Infection in Developing Countries, 2022 Introduction: Viral load measurement is an important gold standard for monitoring anti-retroviral treatment among people living with human immunodeficiency virus.
Elizabeth L Moirana +6 more
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
MethodsX, 2023 Measures of viremic exposure over time, including HIV viral copy-years or durable viremic suppression, may be more relevant measures of viral load exposure for comorbid outcomes and mortality than single time point viral load measures. However, there are
Benjamin W. Barrett +5 more
doaj
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Potential Pitfalls in Estimating Viral Load Heritability [PDF]
Trends in Microbiology, 2016 AbstractIn HIV patients, the set-point viral load (SPVL) is the most widely used predictor of disease severity. Yet SPVL varies over several orders of magnitude between patients. The heritability of SPVL quantifies how much of the variation in SPVL is due to transmissible viral genetics.
Gabriel E. Leventhal +2 more
openaire +4 more sources
Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe [PDF]
, 2017 HIV-1 set-point viral load—the approximately stable value of viraemia in the first years of chronic infection—is a strong predictor of clinical outcome and is highly variable across infected individuals.
Albert, J +29 more
core +9 more sources