Results 91 to 100 of about 253,930 (319)

Nonlinear relationship between viral load and TCT in single/multiple HPV52 infection

Virology Journal
Purpose To determine the correlation between HPV (human papillomavirus) 52 viral load, multiple infections and ThinPrep cytology test (TCT), to inform clinical management of HPV52-positive women after cervical cancer screening.
Bingbing Ma, Jie Zhou, Weijuan Zhou, Zhanzhong Ma, Juan Chen, Hongbo Hu   +5 more
doaj   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Viral air load due to sedimenting and evaporating droplets produced by speaking [PDF]

arXiv, 2020
The effect of evaporation on droplet sedimentation times is crucial for estimating the risk of infection from virus-containing airborne droplets. For droplet radii in the range 100 nm < R < 60 {\mu}m, evaporation can be described in the stagnant-flow approximation and is diffusion limited.
arxiv  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

A simulation model for longitudinal HIV viral load and mother-to-child-transmission in pregnant and postpartum women [PDF]

arXiv, 2019
This manuscript describes the model specification, including input and output measures, dependencies, and structure for VLSiM-PPW, a Monte Carlo type model for HIV adherence, viral load and vertical transmission in pregnant and breastfeeding women.
arxiv  

Within host dynamics of SARS-CoV-2 in humans: Modeling immune responses and antiviral treatments [PDF]

arXiv, 2020
In December 2019, a newly discovered SARS-CoV-2 virus was emerged from China and propagated worldwide as a pandemic. In the absence of preventive medicine or a ready to use vaccine, mathematical models can provide useful scientific insights about transmission patterns and targets for drug development.
arxiv  

Fecal Viral Load and Norovirus-associated Gastroenteritis

Emerging Infectious Diseases, 2006
We report the median cDNA viral load of norovirus genogroup II is >100-fold higher than that of genogroup I in the fecal specimens of patients with norovirus-associated gastroenteritis. We speculate that increased cDNA viral load accounts for the higher transmissibility of genogroup II strains through the fecal-oral route.
Joseph J.Y. Sung, Raymond Lai, Wai K. Leung, Paul K.S. Chan, Martin C.W. Chan, Rebecca K.Y. Lam, Nelson Lee   +6 more
openaire   +4 more sources

Viral Load and Crimean-Congo Hemorrhagic Fever

Emerging Infectious Diseases, 2007
To the Editor: Crimean-Congo hemorrhagic fever (CCHF) is a severe viral disease transmitted to humans by tick bite or contact with blood, excreta, or tissues of infected patients or livestock. The disease is endemic in many African, Asian, and European countries. Sporadic cases or outbreaks have been observed in the Balkan Peninsula (1–5).
Christian Drosten, Marcus Panning, Evangelia Papadimitriou, Majlinda Kota, Enkelejda Velo, Silvia Bino, Arjan Harxhi, Antonis Antoniadis, Anna Papa   +8 more
openaire   +4 more sources

Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita, Neel Desai, Abigail R. Manning, Caitlin Pileggi, Sara Manning Peskin, Danielle K. Sandsmark, Dennis L. Kolson, Matthew K. Schindler   +7 more
wiley   +1 more source