Results 121 to 130 of about 3,662,996 (361)

Applicability of Hepatitis C Virus RNA Viral Load Thresholds for 8-Week Treatments in Patients With Chronic Hepatitis C Virus Genotype 1 Infection [PDF]

, 2016
Johannes Vermehren, Benjamin Maasoumy, Raoel Maan, Gavin Cloherty, C. Berkowski, Jordan J. Feld, Markus Cornberg, Jean–Michel Pawlotsky, Stefan Zeuzem, Michael P. Manns, Christoph Sarrazin, Heiner Wedemeyer   +11 more
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study

Lancet. Infectious Diseases (Print), 2020
K. To, O. Tsang, W. Leung, A. Tam, Tak-chiu Wu, D. Lung, C. Yip, Jian-Piao Cai, J. Chan, T. Chik, Daphne Pui-Ling Lau, Chris Yau-Chung Choi, Lin-lei Chen, W. Chan, Kwok-Hung Chan, J. D. Ip, A. C. Ng, R. W. Poon, Cuiting Luo, V. Cheng, J. Chan, I. Hung, Zhiwei Chen, Honglin Chen, K. Yuen   +24 more
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Reduction of SARS-CoV-2 salivary viral load with pre-procedural mouth rinses: a randomised, controlled, clinical trial [PDF]

, 2023
Jaspreet Farmaha, Jeffrey N. James, Kyle Frazier, Nikhil Sahajpal, Ashis K. Mondal, Doan T. Bloomquist, Ravindra Kolhe, Stephen W. Looney, Ryan F. Bloomquist   +8 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

HPV16/HPV58 viral load is non-linearly correlated with cervical lesions and can be used as a triage marker

Infectious Agents and Cancer
The significance of viral load from high-risk human papillomavirus (HR-HPV) in the detection of cervical lesions is still debated. This study aims to assess the correlation between the viral load of the most common high-risk genotypes (HPV16, HPV18 ...
Jie Zhou, Bingbing Ma, Jinjin Ji, Jianhong Liao, Hongyan Xu, Hongbo Hu   +5 more
doaj   +1 more source

HIV Viral Load PCR Measurement [PDF]

, 2020
National Cancer Institute
openalex   +1 more source