Results 121 to 130 of about 253,930 (319)
Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source
Should public health policy exempt cases with low viral load from isolation during an epidemic?: a modelling study [PDF]
arXivDuring the COVID-19 pandemic, case isolation emerged as a key non-pharmaceutical intervention in pandemic response. Its effectiveness hinges on the timing of isolation, which is often dictated by the onset of contagiousness. While minimizing isolation delays is crucial, the impact of evolving epidemic dynamics, such as changes in viral load ...
arxiv
Optimal Therapy of Hepatitis C Dynamics and Sampling Based Analysis [PDF]
arXiv, 2011 We examine two models for hepatitis C viral (HCV) dynamics, one for monotherapy with interferon (IFN) and the other for combination therapy with IFN and ribavirin. Optimal therapy for both the models is determined using the steepest gradient method, by defining an objective functional which minimizes the infected hepatocyte levels, virion population ...
arxiv
In Vivo Tropism of Hepatitis C Virus Genomic Sequences in Hematopoietic Cells: Influence of Viral Load, Viral Genotype, and Cell Phenotype [PDF]
, 1998 Hervé Lerat +6 more
openalex +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
Advanced Healthcare Materials, EarlyView.This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold +2 more
wiley +1 more source
HIV-1 viral load and CD4 cell count in untreated children with vertically acquired asymptomatic or mild disease [PDF]
, 1998 Paediatric European Network for Treatment of AIDS
openalex +1 more source
Metal–Organic Framework‐Based Antimicrobial Touch Surfaces to Prevent Cross‐Contamination
Advanced Materials, EarlyView.A MOF‐based antimicrobial door handle cover is developed. It completely inhibits the cross‐contamination of Gram‐positive bacterial species (Staphylococcus aureus, and Enterococcus faecalis), Gram‐negative bacterial species (Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii), and fungi (Candida albicans). Abstract Infection diseases
Javier Fonseca +8 more
wiley +1 more source
BMC Infectious DiseasesBackground Early diagnosis of HIV infection decreases the time from HIV diagnosis to viral suppression and reduces further HIV transmission. The Chinese Guidelines for the Diagnosis and Treatment of HIV/AIDS (2021 edition) state that an HIV RNA level > 5,
Li Li +9 more
doaj +1 more source
Feline herpesvirus 1 viral load related to environmental factors in sheltered cats
Ciência Rural: Shelter environment stress factors are related to FHV-1 viral reactivation. However, comparisons between conjunctival viral load and environmental factors have not been commonly evaluated.
Natasha Baumworcel +5 more
doaj +1 more source