Results 11 to 20 of about 253,930 (319)

Modelling upper respiratory viral load dynamics of SARS-CoV-2

BMC Medicine, 2022
Relationships between viral load, severity of illness, and transmissibility of virus are fundamental to understanding pathogenesis and devising better therapeutic and prevention strategies for COVID-19. Here we present within-host modelling of viral load
Joseph D. Challenger, Cher Y. Foo, Yue Wu, Ada W. C. Yan, Mahdi Moradi Marjaneh, Felicity Liew, Ryan S. Thwaites, Lucy C. Okell, Aubrey J. Cunnington   +8 more
doaj   +1 more source

A joint Bayesian hierarchical model for estimating SARS-CoV-2 diagnostic and subgenomic RNA viral dynamics and seroconversion [PDF]

, 2023
Understanding the viral dynamics and immunizing antibodies of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for devising better therapeutic and prevention strategies for COVID-19. Here, we present a Bayesian hierarchical model that jointly estimates the diagnostic RNA viral load reflecting genomic materials of SARS-CoV-2 ...
arxiv   +1 more source

Viral Load Distribution in SARS Outbreak [PDF]

Emerging Infectious Diseases, 2005
An unprecedented community outbreak of severe acute respiratory syndrome (SARS) occurred in the Amoy Gardens, a high-rise residential complex in Hong Kong. Droplet, air, contaminated fomites, and rodent pests have been proposed to be mechanisms for transmitting SARS in a short period.
Chung-Ming Chu, Kwok-Yung Yuen, Kwok-Hung Chan, Kin Sang Chan, Ivan Hung, Vincent C.C. Cheng, Thomas Tsang, Bone S.F. Tang   +7 more
openaire   +4 more sources

An SIR-like kinetic model tracking individuals' viral load [PDF]

Netw. Heterog. Media, 17(3):467-494, 2022, 2021
Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load of each infectious individual.
arxiv   +1 more source

Viral Load Suppression after Enhanced Adherence Counseling and Its Predictors among High Viral Load HIV Seropositive People in North Wollo Zone Public Hospitals, Northeast Ethiopia, 2019: Retrospective Cohort Study

AIDS Research and Treatment, 2020
Background. The World Health Organization currently encourages enhanced adherence counseling for human immunodeficiency virus (HIV) seropositive people with a high viral load count before a treatment switch to the second-line regimen, yet little is known
Gedefaw Diress, Samuel Dagne, Birhan Alemnew, Seteamlak Adane, Amanuel Addisu   +4 more
doaj   +1 more source

Viral load detection and management on first line ART in rural Rwanda

BMC Infectious Diseases, 2019
Background To achieve the ambitious 90–90-90 UNAIDS targets, access to routine viral load (VL) is critical. To measure VL, Rwanda has relied on a national reference laboratory for years.
Jean de Dieu Ndagijimana Ntwali, Tom Decroo, Muhayimpundu Ribakare, Athanase Kiromera, Placidie Mugwaneza, Sabin Nsanzimana, Lutgarde Lynen   +6 more
doaj   +1 more source

Suppression of HIV in the first 12 months of antiretroviral therapy: a comparative analysis of dolutegravir- and efavirenz-based regimens [PDF]

Einstein (São Paulo), 2023
Objective To compare viral suppression in treatment-naïve adults starting antiretroviral therapy with dolutegravir (50mg)- and efavirenz (600mg)-based regimens.
Gabriella Jomara da Silva, Cássia Cristina Pinto Mendicino, Cristiane Aparecida Menezes de Pádua, Unaí Tupinambás   +3 more
doaj   +1 more source

How reliable is an undetectable viral load? [PDF]

HIV Medicine, 2009
Objectives An article by the Swiss AIDS Commission states that patients with stably suppressed viraemia [i.e. several successive HIV‐1 RNA plasma concentrations (viral loads, VL) below the limits of detection during 6 months or more of highly active antiretroviral therapy (HAART)] are unlikely to be infectious.
Combescure, Christophe, Vallier, N., Ledergerber, B., Cavassini, M., Furrer, H., Rauch, A., Battegay, M., Bernasconi, E., Vernazza, P., Hirschel, B.   +9 more
openaire   +4 more sources

Initial viral load and the outcomes of SARS [PDF]

Canadian Medical Association Journal, 2004
Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus. It may progress to respiratory failure, and a significant proportion of patients die. Preliminary data suggest that a high viral load of the SARS coronavirus is associated with adverse outcomes in the intensive care unit, but the relation of viral load to survival is unclear.We ...
Chan, KH, Peiris, JSM, Poon, LLM, Hung, IFN, Yuen, KY, Tse, DMW, Law, KI, Ng, PW, Sim, TC, Ng, WL, Chan, VL, Tang, BSF, Leung, WS, Wong, MML, Chan, KS, Cheng, VCC, Chu, CM   +16 more
openaire   +5 more sources

The relationship between COVID‐19 viral load and disease severity: A systematic review

Immunity, Inflammation and Disease, 2022
Introduction Patients with COVID‐19 may present different viral loads levels. However, the relationship between viral load and disease severity in COVID‐19 is still unknown.
Omid Dadras, Amir M. Afsahi, Zahra Pashaei, Hengameh Mojdeganlou, Amirali Karimi, Pedram Habibi, Alireza Barzegary, Amirata Fakhfouri, Pegah Mirzapour, Nazanin Janfaza, Soheil Dehghani, Fatemeh Afroughi, Mohsen Dashti, Sepideh Khodaei, Esmaeil Mehraeen, Fabricio Voltarelli, Jean‐Marc Sabatier, SeyedAhmad SeyedAlinaghi   +17 more
doaj   +1 more source