Results 221 to 230 of about 436,526 (334)

Viral-load kinetics in post-transplantation cytomegalovirus infections [PDF]

, 2000
Румен Стефанов, Borislav D. Dimitrov   +1 more
openalex   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

The effect of COVID-19 vaccination on viral load among health care workers: a retrospective cohort study. [PDF]

Clin Exp Vaccine Res
Motamed H, Siami S, Abdan Z, Mozafari F, Khazaei S, Habibi R, Rezaeian S, Heydarpour F.   +7 more
europepmc   +1 more source

Growth Velocity, Fat-Free Mass and Energy Intake Are Inversely Related to Viral Load in HIV-Infected Children

, 2000
Stephen M. Arpadi, Patricia A. Cuff, Donald P. Kotler, Jack Wang, Marukh Bamji, Michael Lange, Richard N. Pierson, Dwight E. Matthews   +7 more
openalex   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Impact of point-of-care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial. [PDF]

J Int AIDS Soc
Lwilla AF, Elsbernd K, Boniface S, Edom R, Mahumane A, Meggi B, Buck WC, Lequechane J, Pereira K, Chiwerengo N, Chale F, Mudenyanga C, Mutsaka D, Mueller M, Ntinginya NE, Taveira N, Hoelscher M, Jani I, Kroidl A, Sabi I, and the LIFE Study Consortium.   +20 more
europepmc   +1 more source

Plasma RNA viral load predicts the rate of CD4 T cell decline and death in HIV-2-infected patients in West Africa

, 2000
Koya Ariyoshi, Shabbar Jaffar, Abraham Alabi, Neil G. Berry, Maarten F. Schim van der Loeff, Sehu Sabally, Pa Tamba N’Gom, Tumani Corrah, Richard S. Tedder, H.C. Whittle   +9 more
openalex   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Cell Count, Viral Load, and Clinical Outcome in Patients with HIV Infection after Highly Active Antiretroviral Therapy [PDF]

, 2000

openalex   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source