Results 231 to 240 of about 466,204 (299)

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques [PDF]

, 2017
Diamond, Michael S, et al,, Fox, Julie M, Sukulpovi-Petty, Soila   +3 more
core   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Enhancing Data-Driven Decision-Making in HIV Care With Viral Load and Early Infant Diagnosis Data Dashboards in Côte d'Ivoire: Qualitative Study.

JMIR Hum Factors
He Y, Kouabenan YR, Assoa PH, Puttkammer N, Gloyd S, Hoffman N, Wagenaar BH, Iiams-Hauser C, Komena P, Kamelan NPF, Pongathie AS, Flowers J, Abiola N, Kohemun N, Amani JK, Adje-Toure C, Perrone LA.   +16 more
europepmc   +1 more source

Predictors of longitudinal viral load suppression among adults receiving first line antiretroviral therapy in Central Ethiopia. [PDF]

Sci Rep
Suwanbamrung C, Abraham A, Asheber M, Jaldo MM, Yakob T.   +4 more
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Correlation Between Radiological Features of Axillary Lymph Nodes with CD4 Count and Plasma Viral Load in Patients with HIV. [PDF]

Tomography
Taskin G, Elmali M, Deveci A, Koc IC.
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Impact of viral load kinetics and recurrent cytomegalovirus infection in kidney transplantation. [PDF]

Front Immunol
Dobrer S, Sherwood KR, Davis K, Lan JH, Gill J, Matic N, Keown PA.   +6 more
europepmc   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Hepatitis B in Ethiopia: viral load, affordability, and patient perspectives at a tertiary hospital in Addis Ababa, Ethiopia. [PDF]

BMC Infect Dis
Dessie K, Diriba R, Fekadu A, Adugna Y, Sisay A.   +4 more
europepmc   +1 more source