Results 151 to 160 of about 131,769 (294)

Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes. [PDF]

, 2003
CD8+ class I-restricted cytotoxic T lymphocytes (CTLs) usually incompletely suppress HIV-1 in vivo, and while analogous partial suppression induces antiretroviral drug-resistance mutations, epitope escape mutations are inconsistently observed.
Ali, Ayub, Brander, Christian, Harlow, Jason D, Kalams, Spyros A, Sarkis, Phuong Thi Nguyen, Walker, Bruce D, Yang, Otto O   +6 more
core  

Thermo‐Fluorescent Bactericidal Quantum Dots Based Smart Multifunctional Textiles via Molecular Surface Engineering and 3D‐Printed Interlocked Architectures

Advanced Healthcare Materials, EarlyView.
A versatile approach is presented for fabricating smart multifunctional textiles by integrating thermo‐fluorescent carbon dot/polymer nanocomposite coatings with 3D‐printed interlocked architectures. The fabrics exhibit temperature‐responsive fluorescence, durable hydrophobicity, strong antibacterial and antioxidant activity, and enhanced UV protection.
Poushali Das, Sayan Ganguly, Parham Khoshbakht Marvi, Misha Muthalali, Fatemeh Parniani, Shiza Hassan, Xiaowu (Shirley) Tang, Seshasai Srinivasan, Amin Reza Rajabzadeh   +8 more
wiley   +1 more source

Factors affecting viral suppression or rebound in people living with HIV and receiving antiretroviral therapy in Ghana

Frontiers in Public Health
IntroductionRegular viral load (VL) testing for people living with HIV (PLWH) is key to attaining the Joint United Nations Program on HIV/AIDS (UNAIDS) Fast-Track 95–95-95 target to end the HIV epidemic by 2030.
Anthony T. Boateng, Anthony T. Boateng, James O. Aboagye, James O. Aboagye, Helena Lamptey, Christopher Z.-Y. Abana, Christopher Z.-Y. Abana, Araba Abaidoo-Myles, Araba Abaidoo-Myles, Darius N. K. Quansah, Darius N. K. Quansah, Seth Agyemang, Seth Agyemang, Yaw Awuku-Larbi, Gloria Ansa, Joseph Oliver-Commey, Vincent Ganu, George B. Kyei, George B. Kyei, George B. Kyei, Peter Puplampu, Evelyn Y. Bonney   +21 more
doaj   +1 more source

Reasons for failure to suppress viral load in patients undergoing antiretroviral therapy

World Journal of Advanced Research and Reviews
Background: Suppressing viral load (VL) is a primary goal of antiretroviral therapy (ART), both for the health of individuals living with HIV and to reduce transmission. However, in the Democratic Republic of Congo (DRC), a significant number of patients do not reach this threshold, which compromises the health gains that have been made.
Nathalie, Mbuyamba Mutombo, Astrid, Lokotshe Kanyama, Dodo, Manda Mukendi, Jirène, Ndjibu Ebondo, Emmanuel, Tshibangu Manyonga, Guy, Kandja Lwamba, Elie, Kabika ya Ntambwe, Odon, Panshi wa Panshi, Jerome, Nyembo Lukamba, Didier, Lubelanu Nkanza, Athy, Kalumba Kambote, Franck, Kasans Tshinyengo, Eric, Kasamba Ilunga, Philomène, Lungu Anzwal   +13 more
openaire   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Characteristics associated with viral suppression among HIV-infected children aged 0-14 years in Mozambique, 2019.

PLoS ONE
The human immunodeficiency virus (HIV) is a global public health problem, disproportionally affecting sub-Saharan African countries including Mozambique.
Neusa Vanessa Fernandes Abdul Fataha, Sandra Gaveta, Jahit Sacarlal, Erika Valeska Rossetto, Cynthia Semá Baltazar, Timothy Allen Kellogg   +5 more
doaj   +1 more source

Poking Pluripotency: Nanoinjection Into Human iPSCs

Advanced Materials, EarlyView.
Nanoinjection into hiPSCs: silicon nanotubes effectively transfect human induced pluripotent stem cells (hiPSCs) with mRNA, enabled by a delayed extracellular matrix application and enhanced surface functionalization. Nanoinjection is demonstrated with several reporter mRNA, including co‐transfection of mCherry and GFP.
Jann Harberts, Vuong Thi Thanh Xuan Ho, Yuqi Yang, Yuan Jiang, Roey Elnathan, Nicolas H. Voelcker   +5 more
wiley   +1 more source

Surface‐Capped Protein Nanoparticles for Nonviral Gene Delivery

Advanced Materials, EarlyView.
ABSTRACT Developing simple, safe, and efficient nonviral delivery systems remains a significant challenge in bioengineering. Nanoparticles offer promising gene delivery capabilities with reduced toxicity; however, long‐standing challenges related to effective plasmid encapsulation and delivery exist.
Fjorela Xhyliu, Yao Yao, Yeongun Ko, Grant Grasman, Jeffery E. Raymond, Albert Chang, Yuxuan Deng, Grant Dominic, Michael Triebwasser, Joerg Lahann   +9 more
wiley   +1 more source