Results 141 to 150 of about 700,286 (324)

Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer.

PLoS Biology, 2020
Matrix proteins are encoded by many enveloped viruses, including influenza viruses, herpes viruses, and coronaviruses. Underneath the viral envelope of influenza virus, matrix protein 1 (M1) forms an oligomeric layer critical for particle stability and ...
Lisa Selzer, Zhaoming Su, Grigore D Pintilie, Wah Chiu, Karla Kirkegaard   +4 more
doaj   +1 more source

Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G [PDF]

, 1999
Herpes simplex virus type I (HSV-1) virions and HSV-1-infected cells bind to human immunoglobulin G (hIgG) via its Fc region. A complex of two surface glycoproteins encoded by HSV-1, gE and gI, is responsible for Fc binding.
Bjorkman, Pamela J., Chapman, Tara L., Joseph, Ian M., Morrison, Sherie L., Raghavan, Malini, You, Il   +5 more
core   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]

, 2006
A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G, Chiu, Charles Y, DeRisi, Joseph L, Eckburg, Paul B, Fischer, Kael, Ganem, Don, Koshy, Anita, Merker, Jason D, Patterson, Bruce K, Rouskin, Silvi, Schnurr, David, Tompkins, Lucy S, Urisman, Anatoly, Yagi, Shigeo   +13 more
core  

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

The matrix protein of rabies virus binds to RelAp43 to modulate NF-κB-dependent gene expression related to innate immunity

Scientific Reports, 2016
The matrix (M) protein of wild isolates of rabies virus such as Tha (M-Tha) was previously shown to be able to interact with RelAp43, a protein of the NF-κB family, and to efficiently suppress NF-κB-dependent reporter gene expression, in contrast with ...
Y. Ben Khalifa, Sophie Luco, Benoit Besson, Florian Sonthonnax, Medhi Archambaud, J. Grimes, F. Larrous, H. Bourhy   +7 more
semanticscholar   +1 more source

Morphogenesis of bullet-shaped rabies virus particles requires a functional interplay between the viral matrix protein and ESCRT-I component TSG101 [PDF]

, 2022
Yukari Itakura, Koshiro Tabata, Takeshi Saito, Kittiya Intaruck, Nijiho Kawaguchi, Mai Kishimoto, Shiho Torii, Shintaro Kobayashi, Naoto Ito, Michiko Harada, Satoshi Inoue, Ken Maeda, Ayato Takada, William W. Hall, Yasuko Orba, Hirofumi Sawa, Michihito Sasaki   +16 more
openalex   +1 more source

Machine‐Learning‐Aided Advanced Electrochemical Biosensors

Advanced Materials, EarlyView.
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan, Roozbeh Siavash Moakhar, Carolina del Real Mata, Max Petkun, Tristan De Iure‐Grimmel, Sripadh Guptha Yedire, Hamed Shieh, Arash Khorrami Jahromi, Sahar Sadat Mahshid, Sara Mahshid   +9 more
wiley   +1 more source

HIV-1 Structural Proteins or Cell-Signaling Factors? That Is the Question!

Current Issues in Molecular Biology
The biological activity of structural HIV-1 proteins is not limited to ensuring a productive viral infection but also interferes with cellular homeostasis through intra- and extracellular signaling activation.
Michele Pellegrino, Francesca Giordano, Francesca De Amicis, Maria Marra, Paola Tucci, Stefania Marsico, Stefano Aquaro   +6 more
doaj   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source