TMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein. [PDF]
Virulence, 2020 Duan Z +8 more
europepmc +1 more source
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
1334. Addition of Nuclear Localization Signal Sequences from Both the HIV-1 Matrix and the HIV-1 Vpr Proteins into a Non-Viral Gene Delivery System Produces Equally Efficient Transfection in Dividing and Growth-Arrested HeLa Cells [PDF]
, 2002 openalex +1 more source
Advanced Materials Interfaces, EarlyView.This study investigates the plasmonic properties and biosensing capabilities of a nanocomposite incorporating Cu and Ag nanoparticles for detecting anti‐DbpA antibodies associated with Lyme disease. The enhanced LSPR response is explained through FDTD simulations of Cu–Ag near‐field interactions and increased surface roughness.
Sanjay Kumar +10 more
wiley +1 more source
Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels
Advanced Materials Interfaces, EarlyView.A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost +9 more
wiley +1 more source
The role of influenza neuraminidase transmembrane domain on budding and virus morphology [PDF]
, 2014 Influenza A virus neuraminidase (NA), a type II transmembrane glycoprotein plays a role in the cleavage of sialic acids and facilitating the release of mature virions from the surface of infected cells. NA has also previously been shown to play a role in
Roddy, Scott, Edward
core
Advanced Materials Interfaces, EarlyView.Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler +4 more
wiley +1 more source
RNA Interference with Measles Virus N, P, and L mRNAs Efficiently Prevents and with Matrix Protein mRNA Enhances Viral Transcription [PDF]
, 2006 Thorsten Reuter +3 more
openalex +1 more source
Advanced Materials Interfaces, EarlyView.Detecting single molecules on large interfaces is challenging due to minimal perturbations on the sensing surface. Some biological systems achieve this feat using amplification mechanisms, but their molecular foundations remain unclear. To investigate, a Design of Experiments (DoE) approach examines how pH and ionic strength in conditioning solutions ...
Michele Catacchio +9 more
wiley +1 more source
Study of the interaction of the matrix protein of the newcastle disease virus with lipid bilayers: implications for the mechanism of viral budding [PDF]
, 2008 Anna Shnyrova
openalex +1 more source