Results 251 to 260 of about 700,286 (324)

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

Advanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu, Sibo Jiang, Ting Shen, Yuan Zhang, Chengbin He, Yun Gao, Liyin Shen, Qiao Jin, Yuting Zhao, Ping Liang, Chaochen Wang, Hongjie Hu, Jin He, Kaicheng Deng, Shuo Wang, Yunhe Chen, Jun Ling, Yang Zhu, Lenan Zhuang   +18 more
wiley   +1 more source

Phosphatidylserine Lateral Organization Influences the Interaction of Influenza Virus Matrix Protein 1 with Lipid Membranes

Journal of Virology, 2017
S. Bobone, Malte Hilsch, Julian Storm, Valentin Dunsing, A. Herrmann, S. Chiantia   +5 more
semanticscholar   +1 more source

Sub-Nucleolar Trafficking of Hendra Virus Matrix Protein Is Regulated by Ubiquitination. [PDF]

Viruses
Zhao T, Gomez FA, David CT, Rootes CL, Stewart CR, Moseley GW, Rawlinson SM.   +6 more
europepmc   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu, Shaobo Kang, Na Lin, Wenqi Zhang, Shiwen Wang, Yuqing Ren, Xiaofan Ding, Jianxiu Yu, Ruiyu Xie   +8 more
wiley   +1 more source

Crystal structure of an orthomyxovirus matrix protein reveals mechanisms for self-polymerization and membrane association

Proceedings of the National Academy of Sciences of the United States of America, 2017
Wenting Zhang, Wenjie Zheng, Y. Toh, Miguel A. Betancourt-Solis, Jiagang Tu, Yanlin Fan, V. Vakharia, Jun Liu, J. McNew, M. Jin, Y. Tao   +10 more
semanticscholar   +1 more source

Evaluation of RT-LAMP for SARS-CoV-2 Detection in Animal Feces. [PDF]

Viruses
Pepper A, Kayastha S, Miller M, Guag J, Tkachenko A, Allender M, Terio K, Wang L.   +7 more
europepmc   +1 more source

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

Advanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo, Yan Wang, Qiudi Liu, Zhaoyang Luo, Xiaomu Tian, Yuquan Wang, Yang Liu, Zhiwei Ning, Yingying Guo, Huiying Gao, Xinyue Wang, Jinglong Feng, Mengmeng Liu, Dina Saifullina, Yixin Zhang, Tengfei Pan, Yu Bian, Tao Ban, Tianyu Li, Yunyan Gu, Haihai Liang   +20 more
wiley   +1 more source

Influenza A virus RNA localisation and the interceding trafficking pathways of the host cell. [PDF]

PLoS Pathog
Bonazza S, Courtney DG.
europepmc   +1 more source

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
wiley   +1 more source

Novel Minimal Absent Words Detected in Influenza A Virus. [PDF]

Viruses
Bigiş EZ, Yıldız E, Tagka A, Pavlopoulou A, Chrousos GP, Geronikolou S.   +5 more
europepmc   +1 more source