Results 21 to 30 of about 300,470 (289)

TfR1 facilitates influenza virus endocytosis and uncoating by interacting with NA and M1 via extracellular and intracellular domains. [PDF]

PLoS Pathogens
An intriguing enigma in virology is the utilization of transferrin receptor 1 (TfR1) by various viruses as an entry portal into host cells, a mechanism that remains relatively underexplored.
Xinchen Wang, Yuanhao Li, Dezhong Ji, Yiming Wang, Xiaoyang Wang, Kangming Guo, Mengyang Wang, Yu Mu, Chen Qin, Tao Yuan, Yuanjie Zhang, Zhiqian Chen, Xingxing Zhu, Xiaohui Zhang, Honghui Jiang, Qiuchen He, Chuanling Zhang, Sulong Xiao, Lihe Zhang, Demin Zhou   +19 more
doaj   +2 more sources

The Human Respiratory Syncytial Virus Matrix Protein Is Required for Maturation of Viral Filaments [PDF]

Journal of Virology, 2012
ABSTRACT An experimental system was developed to generate infectious human respiratory syncytial virus (HRSV) lacking matrix (M) protein expression (M-null virus) from cDNA. The role of the M protein in virus assembly was then examined by infecting HEp-2 and Vero cells with the M-null virus and assessing the impact on infectious virus ...
Ruchira Mitra, Pradyumna Baviskar, Rebecca R. Duncan-Decocq, Darshna Patel, Antonius G. P. Oomens   +4 more
openalex   +4 more sources

TMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein. [PDF]

Virulence, 2020
Duan Z, Yuan C, Han Y, Zhou L, Zhao J, Ruan Y, Chen J, Ni M, Ji X.   +8 more
europepmc   +3 more sources

The Ebola Virus Matrix Protein VP40 Interacts With Several Host Protein Networks to Facilitate Viral Replication [PDF]

Current Clinical Microbiology Reports, 2015
The Ebola virus (EBOV) is a lipid-enveloped virus that is filamentous in shape and belongs to the Filoviridae family. EBOV can cause viral hemorrhagic fever in humans and non-human primates with high rates of fatality. Using a negative sense RNA genome that encodes just eight proteins, the lipid-enveloped EBOV can enter mammalian cells and undergo ...
Cary T. Frick, Robert V. Stahelin
openalex   +2 more sources

Involvement of a tick-borne orthomyxovirus matrix protein in vRNP nuclear export [PDF]

Journal of Virology
Thogotoviruses are arthropod-borne viruses belonging to the genus Thogotovirus within the family Orthomyxoviridae. Like other orthomyxoviruses, such as the influenza A viruses (IAV), thogotoviruses replicate in the nucleus.
Vaille A. Swenson, Jack Hemsath, Iris Yousaf, Carla Weisend, Michael A. Barry, Hideki Ebihara, Satoko Yamaoka   +6 more
doaj   +2 more sources

ROLE OF HOST CELL GLYCOLYTIC PROTEINS; ALPHA ENOLASE AND PYRUVATE KINASE IN INFLUENZA A VIRUS INFECTED CELLS

International Journal of Infectious Diseases, 2023
Intro: Influenza A virus, a respiratory pathogen known to manipulate various cellular metabolic processes including glycolysis. Our earlier studies demonstrated the interaction of influenza A viral structural proteins; nucleoprotein and matrix protein ...
P. Goyal, M.S. Rajala
doaj   +1 more source

The Cytoplasmic Tail of Influenza A Virus Hemagglutinin and Membrane Lipid Composition Change the Mode of M1 Protein Association with the Lipid Bilayer

Membranes, 2021
Influenza A virus envelope contains lipid molecules of the host cell and three integral viral proteins: major hemagglutinin, neuraminidase, and minor M2 protein.
Larisa V. Kordyukova, Petr V. Konarev, Nataliya V. Fedorova, Eleonora V. Shtykova, Alexander L. Ksenofontov, Nikita A. Loshkarev, Lubov A. Dadinova, Tatyana A. Timofeeva, Sergei S. Abramchuk, Andrei V. Moiseenko, Lyudmila A. Baratova, Dmitri I. Svergun, Oleg V. Batishchev   +12 more
doaj   +1 more source

In-Silico Approaches for Molecular Characterization and Structure-Based Functional Annotation of the Matrix Protein from Nipah henipavirus 

Chemistry Proceedings, 2022
Nipah henipavirus is an emerging RNA virus that poses a danger to world safety due to its high fatality rate. The Nipah virus has caused several illness epidemics in South and Southeast Asia.
Abu Saim Mohammad Saikat, Apurbo Kumar Paul, Dipta Dey, Ranjit Chandra Das, Madhab Chandra Das   +4 more
doaj   +1 more source

Epitope-based peptide vaccine against Bombali Ebolavirus viral protein 40: An immunoinformatics combined with molecular docking studies

Informatics in Medicine Unlocked, 2021
Bombali Ebolavirus belongs to the RNA group of viruses which causes lethal hemorrhagic fever with a high mortality rate. Despite these facts, yet there is no approved vaccine have been developed for the eradication of Bombali Ebolavirus infections ...
Mujahed I. Mustafa, Shaza W. Shantier, Miyssa I. Abdelmageed, Abdelrafie M. Makhawi   +3 more
doaj   +1 more source

Polyamine-metabolizing enzymes are activated to promote the proper assembly of rice stripe mosaic virus in insect vectors

Stress Biology, 2022
Both viruses and host cells compete for intracellular polyamines for efficient propagation. Currently, how the key polyamine-metabolizing enzymes, including ornithine decarboxylase 1 (ODC1) and its antizyme 1 (OAZ1), are activated to co-ordinate viral ...
Dongsheng Jia, Huan Liu, Jian Zhang, Wenqiang Wan, Zongwen Wang, Xiaofeng Zhang, Qian Chen, Taiyun Wei   +7 more
doaj   +1 more source