The Deoptimization of Rabies Virus Matrix Protein Impacts Viral Transcription and Replication [PDF]
Viruses, 2019 Rabies virus (RABV) matrix (M) protein plays several important roles during RABV infection. Although previous studies have assessed the functions of M through gene rearrangements, this interferes with the position of other viral proteins. In this study, we attenuated M expression through deoptimizing its codon usage based on codon pair bias in RABV ...
Jun Luo +9 more
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The Minor Matrix Protein VP24 from Ebola Virus Lacks Direct Lipid-Binding Properties
Viruses, 2020 Viral protein 24 (VP24) from Ebola virus (EBOV) was first recognized as a minor matrix protein that associates with cellular membranes. However, more recent studies shed light on its roles in inhibiting viral genome transcription and replication ...
Yuan Su, Robert V. Stahelin
doaj +1 more source
Matrix protein Osteonectin (SPARC) reduces inflammation and mortality during viral myocarditis [PDF]
European Heart Journal, 2013 Rationale: Acute viral myocarditis (VM) is one of the leading causes of heart failure in young adults, lacking specific therapy. Osteonection (SPARC) is a non-structural matrix protein modulating cell-matrix interaction in the heart, and has been implicated in cardiac remodeling.
M. Rienks +6 more
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The Matrix Protein of Vesicular Stomatitis Virus Binds Dynamin for Efficient Viral Assembly [PDF]
Journal of Virology, 2010 ABSTRACT Matrix proteins (M) direct the process of assembly and budding of viruses belonging to the Mononegavirales order. Using the two-hybrid system, the amino-terminal part of vesicular stomatitis virus (VSV) M was shown to interact with dynamin pleckstrin homology domain. This interaction was confirmed
Hélène, Raux +5 more
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Viruses, 2021 Measles virus (MV) can cause severe acute diseases as well as long-lasting clinical deteriorations due to viral-induced immunosuppression and neuronal manifestation.
Johannes Busch +4 more
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Role of Viral Hemorrhagic Septicemia Virus Matrix (M) Protein in Suppressing Host Transcription [PDF]
Journal of Virology, 2017 ABSTRACT Viral hemorrhagic septicemia virus (VHSV) is a pathogenic fish rhabdovirus found in discrete locales throughout the Northern Hemisphere. VHSV infection of fish cells leads to upregulation of the host's virus detection response, but the virus quickly suppresses interferon (IFN) production and antiviral gene expression.
Ke, Qi +11 more
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Viruses, 2014 Paramyxoviruses are a family of negative sense RNA viruses whose members cause serious diseases in humans, such as measles virus, mumps virus and respiratory syncytial virus; and in animals, such as Newcastle disease virus and rinderpest virus ...
Farah El Najjar +2 more
doaj +1 more source
ANP32B is a nuclear target of henipavirus M proteins. [PDF]
PLoS ONE, 2014 Membrane envelopment and budding of negative strand RNA viruses (NSVs) is mainly driven by viral matrix proteins (M). In addition, several M proteins are also known to be involved in host cell manipulation.
Anja Bauer +10 more
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In-Silico Approaches for Molecular Characterization, Structural Function Prediction and Peptide Toxicity Analysis of the Matrix Protein of Vesicular stomatitis Indiana Virus (VSIV) [PDF]
BIO Web of ConferencesVesicular Stomatitis Indiana Virus (VSIV) is a primary RNA virus studied for its effects in virology and in biotechnology the matrix protein of VSIV is key in linking the viral envelope to the core which is essential role in the assembly and release of ...
S Ramya +3 more
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Host Desmin Interacts with RABV Matrix Protein and Facilitates Virus Propagation
Viruses, 2023 Microfilaments and microtubules, two crucial structures of cytoskeletal networks, are usurped by various viruses for their entry, egress, and/or intracellular trafficking, including the Rabies virus (RABV).
Wen Zhang +6 more
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