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The Interactions of Viral Matrix Proteins with Membranes [PDF]

Biophysical Journal, 2011
Matrix proteins form the main structure of an enveloped virus, connecting the nucleocapsid to the phospholipid membrane. We have studied the M1 proteins from HRSV and Influenza A to determine their structural characteristics and the nature of their lipid binding.
James A. Freeth, John M. Sanderson, Paul Yeo   +2 more
openaire   +2 more sources

In-Silico Approaches for Molecular Characterization and Structure-Based Functional Annotation of the Matrix Protein from Nipah henipavirus 

Chemistry Proceedings, 2022
Nipah henipavirus is an emerging RNA virus that poses a danger to world safety due to its high fatality rate. The Nipah virus has caused several illness epidemics in South and Southeast Asia.
Abu Saim Mohammad Saikat, Apurbo Kumar Paul, Dipta Dey, Ranjit Chandra Das, Madhab Chandra Das   +4 more
doaj   +1 more source

Polyamine-metabolizing enzymes are activated to promote the proper assembly of rice stripe mosaic virus in insect vectors

Stress Biology, 2022
Both viruses and host cells compete for intracellular polyamines for efficient propagation. Currently, how the key polyamine-metabolizing enzymes, including ornithine decarboxylase 1 (ODC1) and its antizyme 1 (OAZ1), are activated to co-ordinate viral ...
Dongsheng Jia, Huan Liu, Jian Zhang, Wenqiang Wan, Zongwen Wang, Xiaofeng Zhang, Qian Chen, Taiyun Wei   +7 more
doaj   +1 more source

The Deoptimization of Rabies Virus Matrix Protein Impacts Viral Transcription and Replication [PDF]

Viruses, 2019
Rabies virus (RABV) matrix (M) protein plays several important roles during RABV infection. Although previous studies have assessed the functions of M through gene rearrangements, this interferes with the position of other viral proteins. In this study, we attenuated M expression through deoptimizing its codon usage based on codon pair bias in RABV ...
Jun Luo, Yue Zhang, Qiong Zhang, Yuting Wu, Boyue Zhang, Meijun Mo, Qin Tian, Jing Zhao, Mingzhu Mei, Xiaofeng Guo   +9 more
openaire   +3 more sources

The Minor Matrix Protein VP24 from Ebola Virus Lacks Direct Lipid-Binding Properties

Viruses, 2020
Viral protein 24 (VP24) from Ebola virus (EBOV) was first recognized as a minor matrix protein that associates with cellular membranes. However, more recent studies shed light on its roles in inhibiting viral genome transcription and replication ...
Yuan Su, Robert V. Stahelin
doaj   +1 more source

Mutated Measles Virus Matrix and Fusion Protein Influence Viral Titer In Vitro and Neuro-Invasion in Lewis Rat Brain Slice Cultures

Viruses, 2021
Measles virus (MV) can cause severe acute diseases as well as long-lasting clinical deteriorations due to viral-induced immunosuppression and neuronal manifestation.
Johannes Busch, Soroth Chey, Michael Sieg, Thomas W. Vahlenkamp, Uwe G. Liebert   +4 more
doaj   +1 more source

Alterations of membrane curvature during influenza virus budding [PDF]

, 2014
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna, Ali, Brown, Bruce, Chen, Enami, Gomez-Puertas, Jeremy Rossman, Johnson, Lai, Leser, Liao, Liu, McCown, McCown, Palese, Pattnaik, Pinto, Rossman, Rossman, Rossman, Rossman, Ruigrok, Schmidt, Takeda, Wang, Wang, Watanabe, Zebedee, Zhang   +29 more
core   +1 more source

Paramyxovirus Glycoprotein Incorporation, Assembly and Budding: A Three Way Dance for Infectious Particle Production

Viruses, 2014
Paramyxoviruses are a family of negative sense RNA viruses whose members cause serious diseases in humans, such as measles virus, mumps virus and respiratory syncytial virus; and in animals, such as Newcastle disease virus and rinderpest virus ...
Farah El Najjar, Anthony P. Schmitt, Rebecca Ellis Dutch   +2 more
doaj   +1 more source

Host Desmin Interacts with RABV Matrix Protein and Facilitates Virus Propagation

Viruses, 2023
Microfilaments and microtubules, two crucial structures of cytoskeletal networks, are usurped by various viruses for their entry, egress, and/or intracellular trafficking, including the Rabies virus (RABV).
Wen Zhang, Yuming Liu, Mengru Li, Jian Zhu, Xiaoning Li, Ting Rong Luo, Jingjing Liang   +6 more
doaj   +1 more source

In-Silico Approaches for Molecular Characterization, Structural Function Prediction and Peptide Toxicity Analysis of the Matrix Protein of Vesicular stomatitis Indiana Virus (VSIV) [PDF]

BIO Web of Conferences
Vesicular Stomatitis Indiana Virus (VSIV) is a primary RNA virus studied for its effects in virology and in biotechnology the matrix protein of VSIV is key in linking the viral envelope to the core which is essential role in the assembly and release of ...
S Ramya, R Shri Varshini, Sri R Poojaa, Prabhu Puniethaa   +3 more
doaj   +1 more source