Results 171 to 180 of about 259,105 (298)

Tetraspanin CD9 Is a Positive Regulator of Filovirus Egress. [PDF]

Viruses
Anand LK, Djurkovic MA, Shepley-McTaggart A, Shtanko O, Harty RN.   +4 more
europepmc   +1 more source

Sialic Acid Sensing via Molecularly Imprinted Polymer on Laser‐Induced Graphene

Advanced Sensor Research, EarlyView.
Sialic acid is an important biomarker for oral and overall health. Salivary levels of sialic acid are linked with oral cancer and other diseases. We develop a point‐of‐care sensor for sialic acid, based on molecularly imprinted aminophenylboronic acid electropolymerized onto laser‐induced graphene.
Alexander V. Shokurov, Max Nobre Supelnic, Carlo Menon   +2 more
wiley   +1 more source

Viral metagenomic analysis of fecal samples from <i>Bos grunniens</i> on the Qinghai-Tibet Plateau reveals novel picornaviruses and diverse CRESS-DNA viruses. [PDF]

Front Cell Infect Microbiol
Chen J, Gong G, Su X, Song X, Zhang J, Wu P, Wang H, Shan T, Zhang W.   +8 more
europepmc   +1 more source

Rapid Pathogenesis Induced by a Vesicular Stomatitis Virus Matrix Protein Mutant: Viral Pathogenesis Is Linked to Induction of Tumor Necrosis Factor Alpha

, 2006
Jean Publicover, Elizabeth Ramsburg, Michael D. Robek, John K. Rose   +3 more
openalex   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Removal of Porcine Endogenous Retroviruses in Decellularized Liver Bioscaffolds. [PDF]

Xenotransplantation
van Hengel EVA, Drabek D, Roest HP, Willemse J, Reniers LJ, Stallmann H, de Jonge J, Grosveld FG, van der Laan LJW, Verstegen MMA.   +9 more
europepmc   +1 more source

Rice Yellow Stunt Nucleorhabdovirus Matrix Protein Mediates Viral Axonal Transport in the Central Nervous System of Its Insect Vector [PDF]

, 2019
Haitao Wang, Juan Wang, Qian Zhang, Tianbao Zeng, Yuemin Zheng, Hongyan Chen, Xiaofeng Zhang, Tàiyún Wèi   +7 more
openalex   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

The structure of the proteins of Camp Hill virus. [PDF]

PLoS One
Thomas S.
europepmc   +1 more source