Results 251 to 260 of about 664,008 (371)

Functional analysis of matrix proteins expressed from cloned genes of measles virus variants that cause subacute sclerosing panencephalitis reveals a common defect in nucleocapsid binding

Journal of Virology, 1993
A. Hirano, M. Ayata, An Wang, T. Wong, A. Gombart   +4 more
semanticscholar   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

A deep learning and molecular modeling approach to repurposing Cangrelor as a potential inhibitor of Nipah virus. [PDF]

Sci Rep
John L, Dcunha L, Ahmed M, Thomas SD, Raju R, Jayanandan A.   +5 more
europepmc   +1 more source

The N-Terminal Matrix Domain of HIV-1 Gag Is Sufficient but Not Necessary for Viral Protein U-Mediated Enhancement of Particle Release through a Membrane-Targeting Mechanism

, 2000
Aparna Deora, Paul Spearman, Lee Ratner
openalex   +1 more source

Rotavirus Enterotoxin NSP4 Binds to the Extracellular Matrix Proteins Laminin-β3 and Fibronectin

Journal of Virology, 2004
J. Boshuizen, J. Rossen, C. Sitaram, F. Kimenai, Y. Simons‐Oosterhuis, C. Laffeber, H. Büller, A. Einerhand   +7 more
semanticscholar   +1 more source

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

Advanced Science, EarlyView.
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang, Jiahui Zou, Yaoming Jin, Chenjun Jiang, Shaoyu Tu, Tong Chen, Jinli Guo, Yanqing Cheng, Meilin Jin, Huanchun Chen, Hongbo Zhou   +10 more
wiley   +1 more source

Mathematical modelling of the role of Langerhans cells in the dynamics of HPV infection. [PDF]

Sci Rep
Basir FA, Blyuss KB, Raezah AA, Rahman B, Alsakaji HJ.   +4 more
europepmc   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

First contact: an interdisciplinary guide into decoding H5N1 influenza virus interactions with glycosaminoglycans in 3D respiratory cell models. [PDF]

Front Cell Infect Microbiol
Hassan M, Kaifer B, Christian T, Quaas XT, Mueller J, Boehm H.   +5 more
europepmc   +1 more source

Borna Disease Virus Matrix Protein Is an Integral Component of the Viral Ribonucleoprotein Complex That Does Not Interfere with Polymerase Activity

, 2006
Geoffrey Chase, Daniel Mayer, Antonia Hildebrand, Ronald Frank, Yohei Hayashi, Keizō Tomonaga, Martin Schwemmle   +6 more
openalex   +1 more source