Results 181 to 190 of about 30,780 (255)

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang   +8 more
wiley   +1 more source

ssRNA bacteriophage metagenomes reveal a diverse set of novel protein families

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract The bacteriophages with single‐stranded RNA (ssRNA) genomes (class Leviviricetes) are among the simplest known viruses that encode only three core proteins: a receptor‐binding protein, a capsid protein, and an RNA‐dependent RNA polymerase. The number of isolated ssRNA phages has remained very low, but the accumulating RNA metagenome data have ...
Jānis Rūmnieks   +3 more
wiley   +1 more source

Viral Metagenomics of the Bharal (<i>Pseudois nayaur</i>) within the Qinghai-Tibet Plateau Revealed Diverse Viruses. [PDF]

open access: yesPol J Microbiol
Zhang E   +10 more
europepmc   +1 more source

Flush With Data (or) Optimizing and Validating the Efficacy of Free and Computationally Simple 16S Metabarcoding Approaches for Use in Wastewater Surveillance

open access: yesEnvironmental Microbiology, Volume 28, Issue 5, May 2026.
Wastewater treatment plant 16S rRNA sequencing data was used to create simulated read sets of known species composition and relative abundances. These sequence sets were used to optimize current 16S metabarcoding analysis pipelines for the complexity of municipal wastewater samples.
Joe Berta   +3 more
wiley   +1 more source

A ‘Genome‐First’ Framework for Next‐Generation Bioinputs: From Functional Mining to Rational Synthetic Microbial Communities

open access: yesEnvironmental Microbiology, Volume 28, Issue 5, May 2026.
I propose a ‘genome‐first’ framework to collapse the phenotypic bottleneck in bioinput discovery. By integrating multi‐layered genome mining and reverse ecology, this paradigm enables the rational design of stable synthetic microbial communities for a data‐driven and sustainable agricultural bioeconomy.
Osiel Silva Gonçalves
wiley   +1 more source

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