Role of Toll-Like Receptors and Th Responses in Viral Myocarditis
Frontiers in Immunology, 2022 Myocarditis is the common cause of sudden cardiac death, dilated cardiomyopathy (DCM) and heart failure (HF) in young adults. The most common type of myocarditis is viral myocarditis (VMC).
S. Zheng, Jian-zeng Dong
semanticscholar +1 more source
Protective role of the cholinergic anti-inflammatory pathway in a mouse model of viral myocarditis. [PDF]
PLoS ONE, 2014 Activation of the cholinergic anti-inflammatory pathway, which relies on the α7nAchR (alpha 7 nicotinic acetylcholine receptor), has been shown to decrease proinflammatory cytokines.
Zheng Cheng +6 more
doaj +1 more source
A case series of desmoplakin cardiomyopathy: a mimic of viral myocarditis
European Heart Journal: Case Reports, 2022 Background Clinical features and imaging presentation of myocarditis can overlap with other inflammatory or arrhythmogenic cardiomyopathies. Desmoplakin (DSP) is an important structural cardiac protein.
K. Rezaei Bookani +6 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2022 Programmed cell death (PCD), including necroptosis, has emerged as a significant pathway in cardiovascular diseases. The infection of viral myocarditis (VMC) could cause cardiomyocytes degeneration, necrosis, and immune-inflammatory myocardial response ...
Jindong Zhou +6 more
semanticscholar +1 more source
Fasudil exerts a cardio‐protective effect on mice with coxsackievirus B3‐induced acute viral myocarditis [PDF]
Cardiovascular Therapeutics, 2018 AIMS To investigate whether there exists a cardio-protective effect of Fasudil, a selective Rho kinase (ROCK) inhibitor, in an experimental murine model of acute viral myocarditis.
Kezhi Dai +10 more
openalex +2 more sources
A proposed role for sepsis in the pathogenesis of myocardial calcification [PDF]
, 2017 Myocardial calcification is a rare and life-threatening condition that is a recognised complication of ischaemic heart disease, cardiac surgery, rheumatic fever and myocarditis.
AROMATARIO, MARIAROSARIA +7 more
core +1 more source
Viral Myocarditis—From Pathophysiology to Treatment
Journal of Clinical Medicine, 2021 The diagnosis of acute and chronic myocarditis remains a challenge for clinicians. Characterization of this disease has been hampered by its diverse etiologies and heterogeneous clinical presentations.
H. Schultheiss +4 more
semanticscholar +1 more source
Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy
Frontiers in Pharmacology, 2018 Current therapeutics options for viral myocarditis are unsatisfactory. Melatonin (MLT), a hormone secreted by the pineal gland and other organs, has protective effects on ischemic heart injury.
Yimiao Sang +13 more
doaj +1 more source
The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: A case report and review of the literature [PDF]
, 2011 Acute myocarditis is one of the most challenging diagnoses and treatments in cardiology. The acute viral myocarditis diagnosis is usually based on high suspicion, history taking, and physical examination.
Amini, A. +8 more
core +2 more sources
Modeling viral infectious diseases and development of antiviral therapies using human induced pluripotent stem cell-derived systems [PDF]
, 2015 The recent biotechnology breakthrough of cell reprogramming and generation of induced pluripotent stem cells (iPSCs), which has revolutionized the approaches to study the mechanisms of human diseases and to test new drugs, can be exploited to generate ...
Barzon, Luisa +6 more
core +2 more sources