Results 31 to 40 of about 830,992 (283)

Viral Myocarditis—From Pathophysiology to Treatment

Journal of Clinical Medicine, 2021
The diagnosis of acute and chronic myocarditis remains a challenge for clinicians. Characterization of this disease has been hampered by its diverse etiologies and heterogeneous clinical presentations.
H. Schultheiss, C. Baumeier, G. Aleshcheva, C. Bock, F. Escher   +4 more
semanticscholar   +1 more source

Dapagliflozin Alleviates Coxsackievirus B3-induced Acute Viral Myocarditis by Regulating the Macrophage Polarization Through Stat3-related Pathways

Inflammation, 2022
Viral myocarditis (VMC), which is most prevalently caused by Coxsackievirus B3 (CVB3) infection, is a serious clinical condition characterized by cardiac inflammation. Dapagliflozin, a kind of sodium glucose co-transporters 2(SGLT-2) inhibitor, exhibited
P. Yan, Xiaoning Song, Joanne Tran, Run-hua Zhou, Xinran Cao, Gang Zhao, Haitao Yuan   +6 more
semanticscholar   +1 more source

Role of Toll-Like Receptors and Th Responses in Viral Myocarditis

Frontiers in Immunology, 2022
Myocarditis is the common cause of sudden cardiac death, dilated cardiomyopathy (DCM) and heart failure (HF) in young adults. The most common type of myocarditis is viral myocarditis (VMC).
S. Zheng, Jian-zeng Dong
semanticscholar   +1 more source

Protective role of the cholinergic anti-inflammatory pathway in a mouse model of viral myocarditis. [PDF]

PLoS ONE, 2014
Activation of the cholinergic anti-inflammatory pathway, which relies on the α7nAchR (alpha 7 nicotinic acetylcholine receptor), has been shown to decrease proinflammatory cytokines.
Zheng Cheng, Ge Li-Sha, Zhao Jing-Lin, Zhang Wen-Wu, Chen Xue-Si, Chen Xing-Xing, Li Yue-Chun   +6 more
doaj   +1 more source

Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditis

bioRxiv, 2021
A significant fraction of sudden death in children and young adults is due to myocarditis, an inflammatory disease of the heart, most often caused by viral infection.
Madhav Mantri, M. Hinchman, David W. McKellar, Michael F. Z. Wang, Shaun T. Cross, J. S. Parker, Iwijn De Vlaminck   +6 more
semanticscholar   +1 more source

A case series of desmoplakin cardiomyopathy: a mimic of viral myocarditis

European Heart Journal: Case Reports, 2022
Background Clinical features and imaging presentation of myocarditis can overlap with other inflammatory or arrhythmogenic cardiomyopathies. Desmoplakin (DSP) is an important structural cardiac protein.
K. Rezaei Bookani, I. Minga, Joshua Wodskow, Jordan Harris, R. Gordon, N. Sarswat, Amit Pursnani   +6 more
semanticscholar   +1 more source

A proposed role for sepsis in the pathogenesis of myocardial calcification [PDF]

, 2017
Myocardial calcification is a rare and life-threatening condition that is a recognised complication of ischaemic heart disease, cardiac surgery, rheumatic fever and myocarditis.
AROMATARIO, MARIAROSARIA, Ashrafian, Hutan, Athanasiou, Thanos, Bower, Guy, CAPPELLETTI, SIMONE, CIALLELLA, Costantino, Harling, Leanne, Lee, Liang Mei   +7 more
core   +1 more source

Necroptosis and Viral Myocarditis: Tumor Necrosis Factor α as a Novel Biomarker for the Diagnosis of Viral Myocarditis

Frontiers in Cell and Developmental Biology, 2022
Programmed cell death (PCD), including necroptosis, has emerged as a significant pathway in cardiovascular diseases. The infection of viral myocarditis (VMC) could cause cardiomyocytes degeneration, necrosis, and immune-inflammatory myocardial response ...
Jindong Zhou, Jing Xu, Peng Li, Shan Sun, Yimiti Kadier, Shiying Zhou, Aijuan Cheng   +6 more
semanticscholar   +1 more source

Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy

Frontiers in Pharmacology, 2018
Current therapeutics options for viral myocarditis are unsatisfactory. Melatonin (MLT), a hormone secreted by the pineal gland and other organs, has protective effects on ischemic heart injury.
Yimiao Sang, Yimiao Sang, Xiaohong Gu, Lulu Pan, Lulu Pan, Chunxiang Zhang, Chunxiang Zhang, Xing Rong, Tingting Wu, Tianhe Xia, Yuechun Li, Lisha Ge, Yuanhai Zhang, Maoping Chu   +13 more
doaj   +1 more source

The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: A case report and review of the literature [PDF]

, 2011
Acute myocarditis is one of the most challenging diagnoses and treatments in cardiology. The acute viral myocarditis diagnosis is usually based on high suspicion, history taking, and physical examination.
Amini, A., Assadi, M., Jallalat, S., Javadi, H., Mogharrabi, M., Nabipour, I., Pourbehi, G., Ravanbod, M., Semnani, S.   +8 more
core   +2 more sources