Results 181 to 190 of about 572,658 (301)

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice [PDF]

open access: yes, 2017
Aagaard   +49 more
core   +2 more sources

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

open access: yesAdvanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang   +12 more
wiley   +1 more source

The Role of Gut Dysbiosis in the Loss of Intestinal Immune Cell Functions and Viral Pathogenesis. [PDF]

open access: yesMicroorganisms, 2023
Fakharian F   +6 more
europepmc   +1 more source

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

open access: yesAdvanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang   +19 more
wiley   +1 more source

Molecular Aspects of Viral Pathogenesis in Emerging SARS-CoV-2 Variants: Evolving Mechanisms of Infection and Host Response. [PDF]

open access: yesInt J Mol Sci
Muntean ST   +7 more
europepmc   +1 more source

Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis. [PDF]

open access: yesCell Host Microbe, 2023
Kehrer T   +39 more
europepmc   +1 more source

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