Results 231 to 240 of about 2,694,187 (254)

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

Advanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing, Ziyi Zhao, Yuhui Yang, Yichen Lin, Yinglin Xuan, Ziyang Wang, Kai Lv, Xiaoxu Zhu, Zhi Zhang, Dong Ma   +9 more
wiley   +1 more source

Single‐Cell Transcriptomic Profiling Identifies B Cell‐Intrinsic Dysregulation of Sphingolipid Biosynthesis and Could Be Improved by Inhibiting UGCG in Primary Immune Thrombocytopenia

Advanced Science, EarlyView.
This study generates the single‐cell atlas of pathogenic B‐cell subset Bc‐5 in ITP. It identifies RUNX3 as a key survival regulator and uncovers sphingolipid‐driven metabolic reprogramming, validating UGCG inhibition as a therapeutic candidate and building a valuable resource for ITP mechanistic and therapeutic exploration.
Dongmei Luo, Yanxia Zhan, Lili Ji, Pengcheng Xu, Pu Chen, Hao Pang, Yunan Ling, Fanli Hua, Xibing Zhuang, Hao Chen, Yunfeng Cheng   +10 more
wiley   +1 more source

Pathogenesis of Hypervirulent Fowl Adenovirus Serotype 4: The Contributions of Viral and Host Factors

Viruses, 2019
Since 2015, severe outbreaks of hepatitis-hydropericardium syndrome (HHS), caused by hypervirulent fowl adenovirus serotype 4 (FAdV-4), have emerged in several provinces in China, posing a great threat to poultry industry. So far, factors contributing to
Jun Zhao, Zeng Wang
exaly   +2 more sources

New Metrics for Evaluating Viral Respiratory Pathogenesis [PDF]

PLoS ONE, 2015
Viral pathogenesis studies in mice have relied on markers of severe systemic disease, rather than clinically relevant measures, to evaluate respiratory virus infection; thus confounding connections to human disease.
Ralph Barıç, Vineet Menachery, Martin Ferris   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Multifaceted Nature of Lipid Droplets in Viral Interactions and Pathogenesis

Microorganisms, 2023
A Cecilia Helguera Repetto, Carlos Cabello-Gutiérrez, Moises Leon Juarez   +2 more
exaly  

Enteric Viral Co-Infections: Pathogenesis and Perspective

Viruses, 2020
Heyde Makimaa, Harshad Ingle, Megan Baldridge   +2 more
exaly  

Exotic viral hepatitis: A review on epidemiology, pathogenesis, and treatment

Journal of Hepatology, 2022
Eric C M van Gorp, Wesley de Jong, Leanne van Leeuwen   +2 more
exaly  

Controversial Effects of Vitamin D and Related Genes on Viral Infections, Pathogenesis, and Treatment Outcomes

Nutrients, 2020
Choongho Lee
exaly  

Extracellular Vesicles in Viral Pathogenesis: A Case of Dr. Jekyll and Mr. Hyde

Life, 2021
Andrey Vasin, Andrey Gorshkov, Lada Purvinsh   +2 more
exaly  

Implications of oxidative stress on viral pathogenesis

Archives of Virology, 2017
Fernanda Caetano Camini, Camila Carla da Silva Caetano, Letícia T. Almeida, C. L. de Brito Magalhães   +3 more
semanticscholar   +1 more source