Results 231 to 240 of about 7,035,314 (359)

An m⁶A methyltransferase confers host resistance by degrading viral proteins through ubiquitination. [PDF]

Nat Commun
Guo J, Zhang T, Xie H, Hu H, Shi C, Zhao Y, Yin J, Xu G, Wu Z, Wang P, Liu J, Liu P, Zhong K, Chen F, Chen J, Yang J.   +15 more
europepmc   +1 more source

Detection by super-resolution microscopy of viral proteins inside bloodborne extracellular vesicles. [PDF]

Extracell Vesicles Circ Nucl Acids, 2023
Singh RK, Santos MF, Herndon C, Gieler BA, Lee I, Chen J, Lorico A.   +6 more
europepmc   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Beyond Infection: The Role of Secreted Viral Proteins in Pathogenesis, Disease Severity and Diagnostic Applications. [PDF]

Cells
Herrera-Moro Huitron L, Cruz-Holguin VJ, Ulloa-Aguilar JM, De Jesús-González LA, Osuna-Ramos JF, Guzmán-Huerta M, de León-Bautista MP, León-Reyes G, García-Cordero J, Cedillo-Barrón L, Cerna-Cortes JF, León-Juárez M.   +11 more
europepmc   +1 more source

Restriction of Viral Replication by Mutation of the Influenza Virus Matrix Protein

, 2002
Teresa Liu, Zhiping Ye
openalex   +1 more source

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

Evolution of BA.2.86 to JN.1 reveals that functional changes in non-structural viral proteins are required for fitness of SARS-CoV-2. [PDF]

J Virol
Tsujino S, Tsuda M, Nao N, Okumura K, Wang L, Oda Y, Mimura Y, Li J, Hashimoto R, Matsumura Y, Suzuki R, Suzuki S, Yoshimatsu K, Nagao M, Ito J, Takayama K, Sato K, Matsuno K, Tamura T, Tanaka S, Fukuhara T, Genotype to Phenotype Japan (G2P-Japan) Consortium.   +21 more
europepmc   +1 more source

The HTLV-1 Rex protein increases the amount of intron-containing viral RNA by inhibition of splicing and degradation

, 1995
Monika Gröne, Ralph Grassmann
openalex   +2 more sources

Harvesting viral proteins.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1999
A, Lucas, G, McFadden
openaire   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source