Adeno-associated virus 9 (AAV9) viral proteins VP1, VP2, and membrane-associated accessory protein (MAAP) differentially influence <i>in vivo</i> transgene expression. [PDF]
Powell SK, McCown TJ.
europepmc +1 more source
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash+9 more
wiley +1 more source
SARS-CoV-2 outbreak: role of viral proteins and genomic diversity in virus infection and COVID-19 progression. [PDF]
Hussein HAM+12 more
europepmc +1 more source
Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng+11 more
wiley +1 more source
Tripartite motif 2b (trim2b) restricts spring viremia of carp virus by degrading viral proteins and negative regulators NLRP12-like receptors. [PDF]
Fang H, Wu XM, Zheng SY, Chang MX.
europepmc +1 more source
The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur+3 more
wiley +1 more source
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania+2 more
wiley +1 more source
Corrigendum: Phylogenetic analysis of the viral proteins VP4/VP7 of circulating human rotavirus strains in China from 2016 to 2019 and comparison of their antigenic epitopes with those of vaccine strains. [PDF]
Mao T+11 more
europepmc +1 more source
This study investigates the plasmonic properties and biosensing capabilities of a nanocomposite incorporating Cu and Ag nanoparticles for detecting anti‐DbpA antibodies associated with Lyme disease. The enhanced LSPR response is explained through FDTD simulations of Cu–Ag near‐field interactions and increased surface roughness.
Sanjay Kumar+10 more
wiley +1 more source
Targeting host-virus interactions: in silico analysis of the binding of human milk oligosaccharides to viral proteins involved in respiratory infections. [PDF]
Mahaboob Ali AA, Vishal A, Nelson EJR.
europepmc +1 more source