Proteomic and functional analyses of the virion transmembrane proteome of cyprinid herpesvirus 3 [PDF]
, 2017 Virion transmembrane proteins (VTPs) mediate key functions in the herpesvirus infectious cycle. Cyprinid herpesvirus 3 (CyHV-3) is the archetype of fish alloherpesviruses. The present study was devoted to CyHV-3 VTPs.
Boutier, Maxime +12 more
core +1 more source
Unpicking the Secrets of African Swine Fever Viral Replication Sites
Viruses, 2021 African swine fever virus (ASFV) is a highly contagious pathogen which causes a lethal haemorrhagic fever in domestic pigs and wild boar. The large, double-stranded DNA virus replicates in perinuclear cytoplasmic replication sites known as viral ...
Sophie-Marie Aicher +3 more
doaj +1 more source
Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus [PDF]
, 2020 Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta ...
Drake, P +3 more
core +1 more source
Expansion of Viral Genomes with Viral Protein Genome Linked Copies
SSRN Electronic Journal, 2022 Virus protein-linked genome (VPg) proteins are required for replication. VPgs are duplicated in a subset of RNA viruses however their roles are not fully understood and the extent of viral genomes containing VPg copies has not been investigated in detail.
Reid, Warsaba +3 more
openaire +2 more sources
THE POSSIBLE COLLISIONS IN VIRUS INFECTION IMMUNODIAGNOSTICS AND VACCINATION
Инфекция и иммунитет, 2016 Antibodies (Ab), especially natural, display multiple specificity not only due to intrinsic conformational dynamics. With computational analysis the distribution of identical and homologous peptides has been studied in surface proteins from RNA and DNA ...
E. P. Kharchenko
doaj +1 more source
Autophagy Proteins in Viral Exocytosis and Anti-Viral Immune Responses [PDF]
Viruses, 2017 Abstract: Autophagy-related (Atg) gene-encoded proteins were originally described for their crucial role in macroautophagy, a catabolic pathway for cytoplasmic constituent degradation in lysosomes. Recently it has become clear that modules of this machinery can also be used to influence endo- and exocytosis.
openaire +4 more sources
Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins [PDF]
Journal of Visualized Experiments, 2017 The goal of this protocol is to isolate herpes simplex virus type 1 (HSV-1) DNA from infected cells for the identification of associated viral and cellular proteins by mass spectrometry. Although proteins that interact with viral genomes play major roles in determining the outcome of infection, a comprehensive analysis of viral genome associated ...
Jill A. Dembowski, Neal A. DeLuca
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Characterisation of a rare, reassortant human G10P[14] rotavirus strain detected in Honduras
Memorias do Instituto Oswaldo CruzBACKGROUND Although first detected in animals, the rare rotavirus strain G10P[14] has been sporadically detected in humans in Slovenia, Thailand, United Kingdom and Australia among other countries. Earlier studies suggest that the strains found in humans
Osbourne Quaye +8 more
doaj +1 more source
CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis
Viruses, 2011 Human immunodeficiency virus (HIV) infection is principally a mucosal disease and the gastrointestinal (GI) tract is the major site of HIV replication. Loss of CD4+ T cells and systemic immune hyperactivation are the hallmarks of HIV infection.
Angelita Rebollo +2 more
doaj +1 more source
Regulation of alphaherpesvirus protein via post-translational phosphorylation
Veterinary Research, 2022 An alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release.
Tong Zhou +18 more
doaj +1 more source