Results 41 to 50 of about 7,035,314 (359)

Viral Hijacking of BET Proteins

open access: yesViruses, 2022
Proteins of the bromodomain and exterminal domain (BET) family mediate critical host functions such as cell proliferation, transcriptional regulation, and the innate immune response, which makes them preferred targets for viruses. These multidomain proteins are best known as transcriptional effectors able to read acetylated histone and non-histone ...
Irene P. Chen, Melanie Ott
openaire   +3 more sources

Regulation of alphaherpesvirus protein via post-translational phosphorylation

open access: yesVeterinary Research, 2022
An alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release.
Tong Zhou   +18 more
doaj   +1 more source

Characterization and subcellular localization of Alongshan virus proteins

open access: yesFrontiers in Microbiology, 2022
Alongshan virus (ALSV) in the Jingmenvirus group within the family Flaviviridae is a newly discovered tick-borne virus associated with human disease, whose genome includes four segments and encodes four structural proteins (VP1a, VP1b, VP2, VP3, and VP4)
Yinghua Zhao   +13 more
doaj   +1 more source

The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation

open access: yesNature Communications, 2018
AbstractArtificial nanoparticles accumulate a protein corona layer in biological fluids, which significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses share many biophysical properties with artificial nanoparticles in extracellular environments and here we show that respiratory syncytial virus (RSV) and herpes
Kariem Ezzat   +25 more
openaire   +8 more sources

THE POSSIBLE COLLISIONS IN VIRUS INFECTION IMMUNODIAGNOSTICS AND VACCINATION

open access: yesИнфекция и иммунитет, 2016
Antibodies (Ab), especially natural, display multiple specificity not only due to intrinsic conformational dynamics. With computational analysis the distribution of identical and homologous peptides has been studied in surface proteins from RNA and DNA ...
E. P. Kharchenko
doaj   +1 more source

Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction

open access: yesFrontiers in Immunology, 2020
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection.
Long-Feng Lu   +17 more
doaj   +1 more source

PARP12 suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins

open access: yesScience Signaling, 2018
Interferon stimulates the ADP-ribosylation–dependent degradation of nonstructural Zika virus proteins necessary for viral replication. Ribosylation restricts infection Type I interferon signaling drives the expression of hundreds of interferon-stimulated
Lili Li   +10 more
semanticscholar   +1 more source

VPDB: Viral Protein Structural Database [PDF]

open access: yesBioinformation, 2011
Viral Protein Database is an interactive database for three dimensional viral proteins. Our aim is to provide a comprehensive resource to the community of structural virology, with an emphasis on the description of derived data from structural biology.
Om Prakash, Sharma   +3 more
openaire   +2 more sources

Antigenic properties of sARs-CoV-2/human/RUs/nsk-FRCFtM-1/2020 coronavirus isolate from a patient in novosibirsk

open access: yesЖурнал инфектологии, 2020
Objective: isolation of coronavirus SARS-CoV-2 from clinical sample of patient with COVID-19 in Novosibirsk; obtaining a purified and inactivated viral antigen and study of its antigenic properties.
A. A. Chepurnov   +9 more
doaj   +1 more source

Unpicking the Secrets of African Swine Fever Viral Replication Sites

open access: yesViruses, 2021
African swine fever virus (ASFV) is a highly contagious pathogen which causes a lethal haemorrhagic fever in domestic pigs and wild boar. The large, double-stranded DNA virus replicates in perinuclear cytoplasmic replication sites known as viral ...
Sophie-Marie Aicher   +3 more
doaj   +1 more source

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