Results 31 to 40 of about 1,229,346 (305)

CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

Viruses, 2011
Human immunodeficiency virus (HIV) infection is principally a mucosal disease and the gastrointestinal (GI) tract is the major site of HIV replication. Loss of CD4+ T cells and systemic immune hyperactivation are the hallmarks of HIV infection.
Angelita Rebollo, Karim Dorgham, Michèle Février   +2 more
doaj   +1 more source

Structural Motifs and Spatial Structures of Helicase (NS3) and RNA-dependent RNA-polymerase (NS5) of a Flavi-like Kindia tick virus (unclassified Flaviviridae)

Вопросы вирусологии, 2023
Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva, A. V. Gladysheva, V. A. Ternovoi, V. B. Loktev   +3 more
doaj   +1 more source

The HTLV-1 Virological Synapse

Viruses, 2010
Human T-lymphotropic virus-1 (HTLV-1) spreads efficiently between T-cells via a tight and highly organized cell-cell contact known as the virological synapse.
Mohamed Nejmeddine, Charles R.M. Bangham
doaj   +1 more source

HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread [PDF]

, 2016
open access articleHIV-1 spreads between CD4 T cells most efficiently through virus-induced cell-cell contacts. To test whether this process potentiates viral spread by activating signaling pathways, we developed an approach to analyze the ...
Jolly, Clare, Len, Alice C.L., Shivkumar, Maitreyi, Starling, Shimona   +3 more
core   +2 more sources

The cytolytic T lymphocyte response to the murine cytomegalovirus [PDF]

, 1984
During the acute cytolytic T lymphocyte (CTL) response of mice to infection with the murine cytomegalovirus two independent populations of activated interleukin-receptive CTL precursors can be demonstrated.
Ada, Beyer, Chantler, Costanzo, Ebeling, Honess, Hudson, Jackson, Kendall, Kim, Koszinowski, Koszinowski, Laemmli, Mulligan, Osborn, Pfizenmaier, Reddehase, Robinson, Sethi, Sethi, Spear, Svedmyr, Ueda, Zinkernagel, Zinkernagel, Zinkernagel   +25 more
core   +1 more source

Regulation of alphaherpesvirus protein via post-translational phosphorylation

Veterinary Research, 2022
An alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release.
Tong Zhou, Mingshu Wang, Anchun Cheng, Qiao Yang, Bin Tian, Ying Wu, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao, Xuming Ou, Sai Mao, Di Sun, Shaqiu Zhang, Dekang Zhu, Juan Huang, Qun Gao, Yanling Yu, Ling Zhang   +18 more
doaj   +1 more source

Characterization and subcellular localization of Alongshan virus proteins

Frontiers in Microbiology, 2022
Alongshan virus (ALSV) in the Jingmenvirus group within the family Flaviviridae is a newly discovered tick-borne virus associated with human disease, whose genome includes four segments and encodes four structural proteins (VP1a, VP1b, VP2, VP3, and VP4)
Yinghua Zhao, Ping Wu, Li Liu, Baohua Ma, Mingming Pan, Yuan Huang, Nianyan Du, Hongyan Yu, Liyan Sui, Ze-Dong Wang, Zhijun Hou, Quan Liu, Quan Liu, Quan Liu   +13 more
doaj   +1 more source

THE POSSIBLE COLLISIONS IN VIRUS INFECTION IMMUNODIAGNOSTICS AND VACCINATION

Инфекция и иммунитет, 2016
Antibodies (Ab), especially natural, display multiple specificity not only due to intrinsic conformational dynamics. With computational analysis the distribution of identical and homologous peptides has been studied in surface proteins from RNA and DNA ...
E. P. Kharchenko
doaj   +1 more source

Unconventional secretion of viral proteins

Seminars in Cell & Developmental Biology, 2018
Although largely less numerous and characterized than bacterial secreted effectors, several viral virulence factors are secreted by virus infected cells. However, their mode of secretion only starts to be studied at the molecular level. Several of these viral effectors are secreted using an unconventional secretion pathway, i.e.
Schatz, Malvina, Tong, Phuoc Bao Viet, Beaumelle, Bruno   +2 more
openaire   +3 more sources

The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state [PDF]

, 2016
Indexación: Web of ScienceWith about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte ...
Alarcon, V, Alvarez, F, De Ferrari, GV, Flores, Y, Hernandez, S, Kann, M, Loyola, A, Rubio, L, Varas-Godoy, M, Villanueva, RA   +9 more
core   +2 more sources