Results 31 to 40 of about 3,041,480 (305)

The Potential of Eukaryotic Cell-Free Systems as a Rapid Response to Novel Zoonotic Pathogens: Analysis of SARS-CoV-2 Viral Proteins

Frontiers in Bioengineering and Biotechnology, 2022
The ongoing pandemic caused by the novel coronavirus (SARS-CoV-2) has led to more than 445 million infections and the underlying disease, COVID-19, resulted in more than 6 million deaths worldwide.
Franziska Ramm, Franziska Ramm, Srujan K. Dondapati, Hoai Anh Trinh, Hoai Anh Trinh, Dana Wenzel, Ruben M. Walter, Ruben M. Walter, Anne Zemella, Stefan Kubick, Stefan Kubick, Stefan Kubick   +11 more
doaj   +1 more source

Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]

, 2008
Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Wiertz, E.J.H.J., Thomas C Mettenleiter, Jacques J Neefjes, Wang, Ying, Koch, J., Mirjam H M Heemskerk, Loch Sandra, Marieke C Verweij, Daus, Franz, Nikolaus Osterrieder, Neefjes, J.J., Tampe, R., Chowdhury, Shafiqul I., Osterrieder, Nikolaus, Loch, S., Edwin Quinten, Rijsewijk, Frans A. M., Quinten, E., Neefjes, Jacques J., Ressing, Maaike E., Lipinska, A.D., Krystyna Bieńkowska-Szewczyk, Verweij Marieke C., Koch Joachim, Danijela Koppers-Lalic, Neefjes Jacques J., Wiertz, Emmanuel J. H. J., Koppers-Lalic, Danijela, Mettenleiter, T.C., Lipińska Andrea D., Rezende Marisa Marcondes, Ressing Maaike E., Emmanuel J H J Wiertz, Lipinska, Andrea D., Tampé Robert, Verweij, M.C., Ressing, M.E., Ying Wang, Wang, Y., Koch, Joachim, Heemskerk, Mirjam H. M., Sandra Loch, Marisa Marcondes Rezende, Tampé, Robert, Daus, F.J., Reits, E.A., Wiertz Emmanuel J. H. J., Shafiqul I Chowdhury, Loch, Sandra, Koppers-Lalic Danijela, Osterrieder, N., Quinten, Edwin, Rezende, M.M., Robert Tampé, Verweij, Marieke C., Joachim Koch, Franz Daus, Mettenleiter Thomas C., Bienkowska-Szewczyk, K., Rijsewijk, F.A.M., Eric A Reits, Heemskerk Mirjam H. M., Mettenleiter, Thomas C., Maaike E Ressing, Reits Eric A., Marcondes Rezende, Marisa, Chowdhury, S.I., Osterrieder Nikolaus, Daus Franz, Quinten Edwin, Koppers-Lalic, D., Reits, Eric A., Bienkowska-Szewczyk, Krystyna, Andrea D Lipińska, Frans A M Rijsewijk, Bieńkowska-Szewczyk Krystyna, Wang Ying, Rijsewijk Frans A. M., Heemskerk, M.H.M., Chowdhury Shafiqul I., Daus, F.   +80 more
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Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction

Frontiers in Immunology, 2020
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection.
Long-Feng Lu, Long-Feng Lu, Zhuo-Cong Li, Zhuo-Cong Li, Can Zhang, Can Zhang, Xiao-Yu Zhou, Xiao-Yu Zhou, Yu Zhou, Yu Zhou, Jing-Yu Jiang, Jing-Yu Jiang, Dan-Dan Chen, Dan-Dan Chen, Shun Li, Shun Li, Yong-An Zhang, Yong-An Zhang   +17 more
doaj   +1 more source

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus [PDF]

, 2010
Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the fusion (F) protein.
Peeters, B.P.H., G. Koch, B. P. H. Peeters, Rottier, P.J.M., Dortmans, J.C.F.M., J. C. F. M. Dortmans, P. J. M. Rottier, Koch, G.   +7 more
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Unravelling the structure of viral replication complexes at super-resolution [PDF]

, 2013
This work was supported by Biotechnology and Biomedical Sciences Research Council grant BB/H018719/1During infection, many RNA viruses produce characteristic inclusion bodies that contain both viral and host components.
Karl J. Oparka, Tilsner, Jens, Jens eTilsner, Johannes Liesche, Johannes eLiesche, Olga Linnik, Liesche, Johannes, Olga eLinnik, Karl eOparka, Oparka, Karl J, Jens Tilsner, Oparka, Karl J., Linnik, Olga, Tilsner, Jens; id_orcid   +13 more
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Antigenic properties of sARs-CoV-2/human/RUs/nsk-FRCFtM-1/2020 coronavirus isolate from a patient in novosibirsk

Журнал инфектологии, 2020
Objective: isolation of coronavirus SARS-CoV-2 from clinical sample of patient with COVID-19 in Novosibirsk; obtaining a purified and inactivated viral antigen and study of its antigenic properties.
A. A. Chepurnov, K. A. Sharshov, E. I. Kazachinskaya, Yu. V. Kononova, E. A. Kazachkova, O. P. Khripko, K. S. Yurchenko, A. Yu. Alekseev, M. I. Voevoda, A. M. Shestopalov   +9 more
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Steve Oroszlan: A Personal Perspective

Viruses, 2021
My memories of Steve go back over 50 years. While precise dates are no longer in my memory bank, circumstances and emotions remain alive and easy to recall.
Raymond Gilden
doaj   +1 more source

Identification of a Plum pox virus CI-Interacting Protein from Chloroplast That Has a Negative Effect in Virus Infection

Molecular Plant-Microbe Interactions, 2006
The cylindrical inclusion (CI) protein of potyviruses is involved in virus replication and cell-to-cell movement. These two processes should rely on multiple plant-virus interactions; however, little is known about the host factors that are involved in ...
I. Jiménez, L. López, J. M. Alamillo, A. Valli, J. A. García   +4 more
doaj   +1 more source

Across the Hall from Pioneers

Viruses, 2021
I was fortunate to be associated with the lab of Stephen Oroszlan at the US National Cancer Institute from ~1982 until his conversion to Emeritus status in 1995.
Alan Rein
doaj   +1 more source

Cowpea mosaic virus 32- and 60-kilodalton replication proteins target and change the morphology of endoplasmic reticulum membranes [PDF]

, 2002
Cowpea mosaic virus (CPMV) replicates in close association with small membranous vesicles that are formed by rearrangements of intracellular membranes. To determine which of the viral proteins are responsible for the rearrangements of membranes and the ...
Lent, J., van, Jan E. Carette, Carette, J.E., MacFarlance, S.A., Jan van Lent, Wellink, J.E., Stuart A. MacFarlane, Ab van Kammen, Joan Wellink, Kammen, A., van   +9 more
core   +1 more source