Results 31 to 40 of about 873,504 (263)

Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction

open access: yesFrontiers in Immunology, 2020
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection.
Long-Feng Lu   +17 more
doaj   +1 more source

Unconventional secretion of viral proteins

open access: yesSeminars in Cell & Developmental Biology, 2018
Although largely less numerous and characterized than bacterial secreted effectors, several viral virulence factors are secreted by virus infected cells. However, their mode of secretion only starts to be studied at the molecular level. Several of these viral effectors are secreted using an unconventional secretion pathway, i.e.
Schatz, Malvina   +2 more
openaire   +3 more sources

Antigenic properties of sARs-CoV-2/human/RUs/nsk-FRCFtM-1/2020 coronavirus isolate from a patient in novosibirsk

open access: yesЖурнал инфектологии, 2020
Objective: isolation of coronavirus SARS-CoV-2 from clinical sample of patient with COVID-19 in Novosibirsk; obtaining a purified and inactivated viral antigen and study of its antigenic properties.
A. A. Chepurnov   +9 more
doaj   +1 more source

Unpicking the Secrets of African Swine Fever Viral Replication Sites

open access: yesViruses, 2021
African swine fever virus (ASFV) is a highly contagious pathogen which causes a lethal haemorrhagic fever in domestic pigs and wild boar. The large, double-stranded DNA virus replicates in perinuclear cytoplasmic replication sites known as viral ...
Sophie-Marie Aicher   +3 more
doaj   +1 more source

Identification of a Plum pox virus CI-Interacting Protein from Chloroplast That Has a Negative Effect in Virus Infection

open access: yesMolecular Plant-Microbe Interactions, 2006
The cylindrical inclusion (CI) protein of potyviruses is involved in virus replication and cell-to-cell movement. These two processes should rely on multiple plant-virus interactions; however, little is known about the host factors that are involved in ...
I. Jiménez   +4 more
doaj   +1 more source

Human immunodeficiency virus type 1: Role of proteins in the context of viral life cycle

open access: yesJournal of Advanced Biotechnology and Experimental Therapeutics, 2022
The Acquired Immunodeficiency Syndrome (AIDS) is a major global pandemic and of paramount public health concern. Over the years, antiretroviral therapy (ART) has emerged as the gold standard of AIDS treatment.
Vikas Jha   +8 more
doaj   +1 more source

Viral Organization of Human Proteins

open access: yesPLoS ONE, 2010
Although maps of intracellular interactions are increasingly well characterized, little is known about large-scale maps of host-pathogen protein interactions. The investigation of host-pathogen interactions can reveal features of pathogenesis and provide a foundation for the development of drugs and disease prevention strategies.
Stefan Wuchty   +2 more
openaire   +4 more sources

Human Endogenous Retrovirus K (HML-2) in Health and Disease

open access: yesFrontiers in Microbiology, 2020
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections in the evolution of primates and account for about 8% of the human genome.
Bei Xue   +6 more
doaj   +1 more source

Characterisation of a rare, reassortant human G10P[14] rotavirus strain detected in Honduras

open access: yesMemorias do Instituto Oswaldo Cruz
BACKGROUND Although first detected in animals, the rare rotavirus strain G10P[14] has been sporadically detected in humans in Slovenia, Thailand, United Kingdom and Australia among other countries. Earlier studies suggest that the strains found in humans
Osbourne Quaye   +8 more
doaj   +1 more source

How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?

open access: yesPathogens, 2019
As with most viruses, mammalian reovirus can be recognized and attacked by the host-cell interferon response network. Similarly, many viruses have developed resistance mechanisms to counteract the host-cell response at different points of this response ...
Delphine Lanoie   +3 more
doaj   +1 more source

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