Results 31 to 40 of about 873,504 (263)
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection.
Long-Feng Lu +17 more
doaj +1 more source
Unconventional secretion of viral proteins
Although largely less numerous and characterized than bacterial secreted effectors, several viral virulence factors are secreted by virus infected cells. However, their mode of secretion only starts to be studied at the molecular level. Several of these viral effectors are secreted using an unconventional secretion pathway, i.e.
Schatz, Malvina +2 more
openaire +3 more sources
Objective: isolation of coronavirus SARS-CoV-2 from clinical sample of patient with COVID-19 in Novosibirsk; obtaining a purified and inactivated viral antigen and study of its antigenic properties.
A. A. Chepurnov +9 more
doaj +1 more source
Unpicking the Secrets of African Swine Fever Viral Replication Sites
African swine fever virus (ASFV) is a highly contagious pathogen which causes a lethal haemorrhagic fever in domestic pigs and wild boar. The large, double-stranded DNA virus replicates in perinuclear cytoplasmic replication sites known as viral ...
Sophie-Marie Aicher +3 more
doaj +1 more source
The cylindrical inclusion (CI) protein of potyviruses is involved in virus replication and cell-to-cell movement. These two processes should rely on multiple plant-virus interactions; however, little is known about the host factors that are involved in ...
I. Jiménez +4 more
doaj +1 more source
Human immunodeficiency virus type 1: Role of proteins in the context of viral life cycle
The Acquired Immunodeficiency Syndrome (AIDS) is a major global pandemic and of paramount public health concern. Over the years, antiretroviral therapy (ART) has emerged as the gold standard of AIDS treatment.
Vikas Jha +8 more
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Viral Organization of Human Proteins
Although maps of intracellular interactions are increasingly well characterized, little is known about large-scale maps of host-pathogen protein interactions. The investigation of host-pathogen interactions can reveal features of pathogenesis and provide a foundation for the development of drugs and disease prevention strategies.
Stefan Wuchty +2 more
openaire +4 more sources
Human Endogenous Retrovirus K (HML-2) in Health and Disease
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections in the evolution of primates and account for about 8% of the human genome.
Bei Xue +6 more
doaj +1 more source
Characterisation of a rare, reassortant human G10P[14] rotavirus strain detected in Honduras
BACKGROUND Although first detected in animals, the rare rotavirus strain G10P[14] has been sporadically detected in humans in Slovenia, Thailand, United Kingdom and Australia among other countries. Earlier studies suggest that the strains found in humans
Osbourne Quaye +8 more
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How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?
As with most viruses, mammalian reovirus can be recognized and attacked by the host-cell interferon response network. Similarly, many viruses have developed resistance mechanisms to counteract the host-cell response at different points of this response ...
Delphine Lanoie +3 more
doaj +1 more source

