Results 41 to 50 of about 1,218,197 (305)

The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation

open access: yesNature Communications, 2018
AbstractArtificial nanoparticles accumulate a protein corona layer in biological fluids, which significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses share many biophysical properties with artificial nanoparticles in extracellular environments and here we show that respiratory syncytial virus (RSV) and herpes
Kariem Ezzat   +25 more
openaire   +8 more sources

THE POSSIBLE COLLISIONS IN VIRUS INFECTION IMMUNODIAGNOSTICS AND VACCINATION

open access: yesИнфекция и иммунитет, 2016
Antibodies (Ab), especially natural, display multiple specificity not only due to intrinsic conformational dynamics. With computational analysis the distribution of identical and homologous peptides has been studied in surface proteins from RNA and DNA ...
E. P. Kharchenko
doaj   +1 more source

Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction

open access: yesFrontiers in Immunology, 2020
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection.
Long-Feng Lu   +17 more
doaj   +1 more source

The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state [PDF]

open access: yes, 2016
Indexación: Web of ScienceWith about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte ...
Alarcon, V   +9 more
core   +2 more sources

VPDB: Viral Protein Structural Database [PDF]

open access: yesBioinformation, 2011
Viral Protein Database is an interactive database for three dimensional viral proteins. Our aim is to provide a comprehensive resource to the community of structural virology, with an emphasis on the description of derived data from structural biology.
Om Prakash, Sharma   +3 more
openaire   +2 more sources

Antigenic properties of sARs-CoV-2/human/RUs/nsk-FRCFtM-1/2020 coronavirus isolate from a patient in novosibirsk

open access: yesЖурнал инфектологии, 2020
Objective: isolation of coronavirus SARS-CoV-2 from clinical sample of patient with COVID-19 in Novosibirsk; obtaining a purified and inactivated viral antigen and study of its antigenic properties.
A. A. Chepurnov   +9 more
doaj   +1 more source

Unpicking the Secrets of African Swine Fever Viral Replication Sites

open access: yesViruses, 2021
African swine fever virus (ASFV) is a highly contagious pathogen which causes a lethal haemorrhagic fever in domestic pigs and wild boar. The large, double-stranded DNA virus replicates in perinuclear cytoplasmic replication sites known as viral ...
Sophie-Marie Aicher   +3 more
doaj   +1 more source

To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes. [PDF]

open access: yes, 2015
Type I interferon (IFN) is one of the first lines of cellular defense against viral pathogens. As a result of IFN signaling, a wide array of IFN-stimulated gene (ISG) products is upregulated to target different stages of the viral life cycle.
Li, Melody MH   +2 more
core   +1 more source

Identification of a Plum pox virus CI-Interacting Protein from Chloroplast That Has a Negative Effect in Virus Infection

open access: yesMolecular Plant-Microbe Interactions, 2006
The cylindrical inclusion (CI) protein of potyviruses is involved in virus replication and cell-to-cell movement. These two processes should rely on multiple plant-virus interactions; however, little is known about the host factors that are involved in ...
I. Jiménez   +4 more
doaj   +1 more source

Human immunodeficiency virus type 1: Role of proteins in the context of viral life cycle

open access: yesJournal of Advanced Biotechnology and Experimental Therapeutics, 2022
The Acquired Immunodeficiency Syndrome (AIDS) is a major global pandemic and of paramount public health concern. Over the years, antiretroviral therapy (ART) has emerged as the gold standard of AIDS treatment.
Vikas Jha   +8 more
doaj   +1 more source

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