The potato mop-top virus TGB2 protein and viral RNA associate with chloroplasts and viral infection induces inclusions in the plastids [PDF]
The potato mop-top virus (PMTV) triple gene block 2 (TGB2) movement proteins fused to monomeric red fluorescent protein (mRFP-TGB2) was expressed under the control of the PMTV subgenomic promoter from a PMTV vector.
Roberts, Alison G. +22 more
core +1 more source
Viral interferon antagonists and antiviral drugs [PDF]
For this project, we developed reporter cell lines that express viral proteins with the potential to be used in cell-based screening assays to select chemical candidates for antiviral drugs.
Nobre, Rita
core +2 more sources
The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation
Abstract Artificial nanoparticles accumulate a protein corona layer in biological fluids, which significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses share many biophysical properties with artificial nanoparticles in extracellular environments and here we show that ...
Kariem Ezzat +25 more
openaire +8 more sources
How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?
As with most viruses, mammalian reovirus can be recognized and attacked by the host-cell interferon response network. Similarly, many viruses have developed resistance mechanisms to counteract the host-cell response at different points of this response ...
Delphine Lanoie +3 more
doaj +1 more source
Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva +3 more
doaj +1 more source
Assembly of Viral Membrane Proteins [PDF]
The generation of computational models is an alternative route to obtain reliable structures for the oligomeric state of membrane proteins. A strategy has been developed to search the conformational space of all possible assemblies in a reasonable time, taking symmetry considerations into account. The methodology tested on M2 from influenza A, shows an
J, Krüger, W B, Fischer
openaire +2 more sources
Acylation of viral and eukaryotic proteins [PDF]
This paper is a review article about post-transcriptionnal modification that occurs in viral and eukaryotic proteins. Acylation obviously plays a role in mediating protein-lipid interactions in targeting and binding polypeptide chains to different types of membrane, but it also seems to be important in mediating protein-protein ...
openaire +2 more sources
Parainfluenza virus 5 genomes are located in viral cytoplasmic bodies whilst the virus dismantles the interferon-induced antiviral state of cells [PDF]
This work was supported by the Wellcome Trust.Although the replication cycle of parainfluenza virus type 5 (PIV5) is initially severely impaired in cells in an interferon (IFN)-induced antiviral state, the virus still targets STAT1 for degradation.
Carlos, T S +5 more
core +1 more source
Regulation of alphaherpesvirus protein via post-translational phosphorylation
An alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release.
Tong Zhou +18 more
doaj +1 more source
Characterization and subcellular localization of Alongshan virus proteins
Alongshan virus (ALSV) in the Jingmenvirus group within the family Flaviviridae is a newly discovered tick-borne virus associated with human disease, whose genome includes four segments and encodes four structural proteins (VP1a, VP1b, VP2, VP3, and VP4)
Yinghua Zhao +13 more
doaj +1 more source

