Results 11 to 20 of about 15,700 (169)

Inhibition of PKR by Viruses

open access: yesFrontiers in Microbiology, 2021
Cells respond to viral infections through sensors that detect non-self-molecules, and through effectors, which can have direct antiviral activities or adapt cell physiology to limit viral infection and propagation.
Teresa Cesaro, Thomas Michiels
doaj   +1 more source

Evasion of interferon-mediated immune response by arteriviruses

open access: yesFrontiers in Immunology, 2022
IFN is the most potent antiviral cytokine required for the innate and adaptive immune responses, and its expression can help the host defend against viral infection.
Zhijie Jian   +14 more
doaj   +1 more source

Influenza B: Prospects for the Development of Cross-Protective Vaccines

open access: yesViruses, 2022
In this review, we analyze the epidemiological and ecological features of influenza B, one of the most common and severe respiratory infections. The review presents various strategies for cross-protective influenza B vaccine development, including ...
Liudmila M. Tsybalova   +3 more
doaj   +1 more source

Viruses and viral proteins

open access: yesIUCrJ, 2014
For more than 30 years X-ray crystallography has been by far the most powerful approach for determining the structures of viruses and viral proteins at atomic resolution.
Nuria Verdaguer   +2 more
doaj   +1 more source

Epitope diversity of SARS-CoV-2 hyperimmune intravenous human immunoglobulins and neutralization of variants of concern

open access: yesiScience, 2021
Summary: Hyperimmune immunoglobulin (hCoV-2IG) generated from SARS-CoV-2 convalescent plasma (CP) are under evaluation in clinical trials. Here we explored the antibody epitope repertoire, and virus neutralizing capacity of six hCoV-2IG batches as well ...
Juanjie Tang   +9 more
doaj   +1 more source

CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

open access: yesViruses, 2011
Human immunodeficiency virus (HIV) infection is principally a mucosal disease and the gastrointestinal (GI) tract is the major site of HIV replication. Loss of CD4+ T cells and systemic immune hyperactivation are the hallmarks of HIV infection.
Angelita Rebollo   +2 more
doaj   +1 more source

The HTLV-1 Virological Synapse

open access: yesViruses, 2010
Human T-lymphotropic virus-1 (HTLV-1) spreads efficiently between T-cells via a tight and highly organized cell-cell contact known as the virological synapse.
Mohamed Nejmeddine, Charles R.M. Bangham
doaj   +1 more source

Structural Motifs and Spatial Structures of Helicase (NS3) and RNA-dependent RNA-polymerase (NS5) of a Flavi-like Kindia tick virus (unclassified Flaviviridae)

open access: yesВопросы вирусологии, 2023
Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva   +3 more
doaj   +1 more source

THE POSSIBLE COLLISIONS IN VIRUS INFECTION IMMUNODIAGNOSTICS AND VACCINATION

open access: yesИнфекция и иммунитет, 2016
Antibodies (Ab), especially natural, display multiple specificity not only due to intrinsic conformational dynamics. With computational analysis the distribution of identical and homologous peptides has been studied in surface proteins from RNA and DNA ...
E. P. Kharchenko
doaj   +1 more source

Regulation of alphaherpesvirus protein via post-translational phosphorylation

open access: yesVeterinary Research, 2022
An alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release.
Tong Zhou   +18 more
doaj   +1 more source

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