Results 11 to 20 of about 1,218,197 (305)
Viruses and viral proteins [PDF]
For more than 30 years X-ray crystallography has been by far the most powerful approach for determining the structures of viruses and viral proteins at atomic resolution.
Nuria Verdaguer +2 more
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This special issue on ‘Viral membrane proteins’ incorporates a series of research articles that were presented at the ‘Conference on Viral Membrane Proteins’, held at the University of Heidelberg, Germany, on 12–14 December 2008. The aim of the symposium was to involve all areas of research in this emerging Weld focusing on biophysical and clinically ...
Wolfgang B. Fischer +2 more
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Membrane activity of viral proteins. [PDF]
COVID-19 infection, caused by the SARS-CoV-2 coronavirus, has led to the largest pandemic since the Spanish flu in 1918. In view of this, the development of vaccines and antiviral drugs that can stop the spread of this infection has become an acute issue. Currently, in the search for antiviral drugs against COVID-19, much attention is paid to the study
Denieva Z.
europepmc +3 more sources
Enteroviruses are members of the Picornaviridae family consisting of human enterovirus groups A, B, C, and D as well as nonhuman enteroviruses. Human enterovirus type 71 (EV71) has emerged as a major cause of viral encephalitis, known as hand, foot, and ...
Subrat Kumar Swain +3 more
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Expansion of Viral Genomes with Viral Protein Genome Linked Copies
Virus protein-linked genome (VPg) proteins are required for replication. VPgs are duplicated in a subset of RNA viruses however their roles are not fully understood and the extent of viral genomes containing VPg copies has not been investigated in detail.
Reid, Warsaba +3 more
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Design of a Multiepitope Vaccine against Chicken Anemia Virus Disease
Chicken anemia virus (CAV) causes severe clinical and sub-clinical infection in poultry globally and thus leads to economic losses. The drawbacks of the commercially available vaccines against CAV disease signal the need for a novel, safe, and effective ...
Abiodun Joseph Fatoba +5 more
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Cells respond to viral infections through sensors that detect non-self-molecules, and through effectors, which can have direct antiviral activities or adapt cell physiology to limit viral infection and propagation.
Teresa Cesaro, Thomas Michiels
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Evasion of interferon-mediated immune response by arteriviruses
IFN is the most potent antiviral cytokine required for the innate and adaptive immune responses, and its expression can help the host defend against viral infection.
Zhijie Jian +14 more
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Assembly of Viral Membrane Proteins [PDF]
The generation of computational models is an alternative route to obtain reliable structures for the oligomeric state of membrane proteins. A strategy has been developed to search the conformational space of all possible assemblies in a reasonable time, taking symmetry considerations into account. The methodology tested on M2 from influenza A, shows an
J, Krüger, W B, Fischer
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Influenza B: Prospects for the Development of Cross-Protective Vaccines
In this review, we analyze the epidemiological and ecological features of influenza B, one of the most common and severe respiratory infections. The review presents various strategies for cross-protective influenza B vaccine development, including ...
Liudmila M. Tsybalova +3 more
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