Results 51 to 60 of about 7,313,460 (355)

Regulation of alphaherpesvirus infections by the ICP0 family of proteins [PDF]

, 2013
Immediate-early protein ICP0 of herpes simplex virus type 1 (HSV-1) is important for the regulation of lytic and latent viral infection. Like the related proteins expressed by other alphaherpesviruses, ICP0 has a zinc-stabilized RING finger domain that ...
Boutell, Chris, Everett, Roger
core   +1 more source

Towards peptide vaccines against Zika virus: Immunoinformatics combined with molecular dynamics simulations to predict antigenic epitopes of Zika viral proteins

Scientific Reports, 2016
The recent outbreak of Zika virus (ZIKV) infection in Brazil has developed to a global health concern due to its likely association with birth defects (primary microcephaly) and neurological complications. Consequently, there is an urgent need to develop
Muhammad Usman Mirza, Shazia Rafique, Amjad Ali, M. Munir, Nazia Ikram, A. Manan, O. Salo-Ahen, M. Idrees   +7 more
semanticscholar   +1 more source

Characterisation of a rare, reassortant human G10P[14] rotavirus strain detected in Honduras

Memorias do Instituto Oswaldo Cruz
BACKGROUND Although first detected in animals, the rare rotavirus strain G10P[14] has been sporadically detected in humans in Slovenia, Thailand, United Kingdom and Australia among other countries. Earlier studies suggest that the strains found in humans
Osbourne Quaye, Sunando Roy, Kunchala Rungsrisuriyachai, Mathew D Esona, Ziqian Xu, Ka Ian Tam, Dina J Castro Banegas, Gloria Rey-Benito, Michael D Bowen   +8 more
doaj   +1 more source

Structural Motifs and Spatial Structures of Helicase (NS3) and RNA-dependent RNA-polymerase (NS5) of a Flavi-like Kindia tick virus (unclassified Flaviviridae)

Вопросы вирусологии, 2023
Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva, A. V. Gladysheva, V. A. Ternovoi, V. B. Loktev   +3 more
doaj   +1 more source

Proteomic analysis of Glossina pallidipes salivary gland hypertrophy virus virions for immune intervention in tsetse fly colonies [PDF]

, 2010
Many species of tsetse flies (Diptera: Glossinidae) can be infected by a virus that causes salivary gland hypertrophy (SGH). The viruses isolated from Glossina pallidipes (GpSGHV) and Musca somestica (MdSGHV) have recently been sequenced.
Abd-Alla, A.M.M., Bergoin, M., Boeren, S., Ince, I.A., Kariithi, H.M., Oers, M.M., van, Vervoort, J.J.M., Vlak, J.M.   +7 more
core   +2 more sources

Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction

Frontiers in Immunology, 2020
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection.
Long-Feng Lu, Long-Feng Lu, Zhuo-Cong Li, Zhuo-Cong Li, Can Zhang, Can Zhang, Xiao-Yu Zhou, Xiao-Yu Zhou, Yu Zhou, Yu Zhou, Jing-Yu Jiang, Jing-Yu Jiang, Dan-Dan Chen, Dan-Dan Chen, Shun Li, Shun Li, Yong-An Zhang, Yong-An Zhang   +17 more
doaj   +1 more source

The role of packaging sites in efficient and specific virus assembly

, 2015
During the lifecycle of many single-stranded RNA viruses, including many human pathogens, a protein shell called the capsid spontaneously assembles around the viral genome. Understanding the mechanisms by which capsid proteins selectively assemble around
Hagan, M. F., Perlmutter, J. D.
core   +1 more source

Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins

Nature Communications, 2016
The ubiquitin-like protein ISG15 and its conjugation to proteins (ISGylation) are strongly induced by type I interferon. Influenza B virus encodes non-structural protein 1 (NS1B) that binds human ISG15 and provides an appropriate model for determining ...
Chen Zhao, Haripriya Sridharan, Ran Chen, Darren P. Baker, Shanshan Wang, R. M. Krug   +5 more
semanticscholar   +1 more source

The Critical Role of Genome Maintenance Proteins in Immune Evasion During Gammaherpesvirus Latency

Frontiers in Microbiology, 2019
Gammaherpesviruses are important pathogens that establish latent infection in their natural host for lifelong persistence. During latency, the viral genome persists in the nucleus of infected cells as a circular episomal element while the viral gene ...
Océane Sorel, Océane Sorel, Benjamin G. Dewals   +2 more
doaj   +1 more source

Characterization and subcellular localization of Alongshan virus proteins

Frontiers in Microbiology, 2022
Alongshan virus (ALSV) in the Jingmenvirus group within the family Flaviviridae is a newly discovered tick-borne virus associated with human disease, whose genome includes four segments and encodes four structural proteins (VP1a, VP1b, VP2, VP3, and VP4)
Yinghua Zhao, Ping Wu, Li Liu, Baohua Ma, Mingming Pan, Yuan Huang, Nianyan Du, Hongyan Yu, Liyan Sui, Ze-Dong Wang, Zhijun Hou, Quan Liu, Quan Liu, Quan Liu   +13 more
doaj   +1 more source