Results 51 to 60 of about 995,700 (356)

The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic antiviral immune response to herpes simplex virus 1 (HSV-1) [PDF]

, 2016
Aspects of intrinsic antiviral immunity are mediated by promyelocytic leukaemia (PML)-nuclear body (PML-NB) constituent proteins. During herpesvirus infection, these antiviral proteins are independently recruited to nuclear domains that contain infecting
Boutell, Chris, Brown, James R., Charman, Matthew, Conn, Kristen L., Grant, Kyle, McFarlane, Steven, Tong, Lily, Wasson, Peter   +7 more
core   +1 more source

Vaccinia Viral Protein A27 Is Anchored to the Viral Membrane via a Cooperative Interaction with Viral Membrane Protein A17 [PDF]

Journal of Biological Chemistry, 2014
The vaccinia viral protein A27 in mature viruses specifically interacts with heparan sulfate for cell surface attachment. In addition, A27 associates with the viral membrane protein A17 to anchor to the viral membrane; however, the specific interaction between A27 and A17 remains largely unclear.
Chien-Hsuan Wong, Da-Rong Wang, Steve S.-F. Yu, Guo-Chian Li, Su-Ching Lin, Jye-Chian Hsiao, Wen Chang, Der-Lii M. Tzou, Wenlung Chen   +8 more
openaire   +3 more sources

Epitope diversity of SARS-CoV-2 hyperimmune intravenous human immunoglobulins and neutralization of variants of concern

iScience, 2021
Summary: Hyperimmune immunoglobulin (hCoV-2IG) generated from SARS-CoV-2 convalescent plasma (CP) are under evaluation in clinical trials. Here we explored the antibody epitope repertoire, and virus neutralizing capacity of six hCoV-2IG batches as well ...
Juanjie Tang, Youri Lee, Supriya Ravichandran, Gabrielle Grubbs, Chang Huang, Charles B. Stauft, Tony Wang, Basil Golding, Hana Golding, Surender Khurana   +9 more
doaj  

The HTLV-1 Virological Synapse

Viruses, 2010
Human T-lymphotropic virus-1 (HTLV-1) spreads efficiently between T-cells via a tight and highly organized cell-cell contact known as the virological synapse.
Mohamed Nejmeddine, Charles R.M. Bangham
doaj   +1 more source

Human Endogenous Retrovirus K (HML-2) in Health and Disease

Frontiers in Microbiology, 2020
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections in the evolution of primates and account for about 8% of the human genome.
Bei Xue, Bei Xue, Leonardo A. Sechi, Leonardo A. Sechi, David J. Kelvin, David J. Kelvin, David J. Kelvin   +6 more
doaj   +1 more source

Evasion of interferon-mediated immune response by arteriviruses

Frontiers in Immunology, 2022
IFN is the most potent antiviral cytokine required for the innate and adaptive immune responses, and its expression can help the host defend against viral infection.
Zhijie Jian, Rui Ma, Ling Zhu, Ling Zhu, Huidan Deng, Fengqin Li, Fengqin Li, Jun Zhao, Jun Zhao, Lishuang Deng, Siyuan Lai, Xiangang Sun, Huaqiao Tang, Zhiwen Xu, Zhiwen Xu   +14 more
doaj   +1 more source

Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]

, 2019
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid, Couck, Liesbeth, Favoreel, Herman, Laval, Kathlyn, Nauwynck, Hans, Poelaert, Katrien, Van Cleemput, Jolien, Van Den Broeck, Wim   +7 more
core   +1 more source

A Comprehensive View on the Host Factors and Viral Proteins Associated With Porcine Epidemic Diarrhea Virus Infection

Frontiers in Microbiology, 2021
Porcine epidemic diarrhea virus (PEDV), a coronavirus pathogen of the pig intestinal tract, can cause fatal watery diarrhea in piglets, thereby causing huge economic losses to swine industries around the world.
Yi Hu, Xiaohong Xie, Lingchen Yang, Aibing Wang, Aibing Wang   +4 more
doaj   +1 more source

Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments [PDF]

, 2009
Previous reports have shown that adenovirus recruits nucleolar protein upstream-binding factor (UBF) into adenovirus DNA replication centres. Here, we report that despite having a different mode of viral DNA replication, herpes simplex virus type 1 (HSV ...
Ahmed, Bertrand, Besse, Boehmer, Boisvert, Cheng, Copenhaver, D. A. Matthews, de Jong, Everett, Grummt, Hiscox, Kuhn, Lawrence, Liu, Lymberopoulos, Mears, Meraner, N. D. Stow, Pederson, Puvion-Dutilleul, Roller, Stow, Strang, Taylor, V. C. Evans   +25 more
core   +2 more sources

Acylation of viral and eukaryotic proteins [PDF]

Biochemical Journal, 1989
This paper is a review article about post-transcriptionnal modification that occurs in viral and eukaryotic proteins. Acylation obviously plays a role in mediating protein-lipid interactions in targeting and binding polypeptide chains to different types of membrane, but it also seems to be important in mediating protein-protein ...
openaire   +3 more sources