Results 61 to 70 of about 928,330 (381)
Dynamical Implications of Viral Tiling Theory [PDF]
Journal of Theoretical Biology 252 (2008) 357-369, 2007 The Caspar-Klug classification of viruses whose protein shell, called viral capsid, exhibits icosahedral symmetry, has recently been extended to incorporate viruses whose capsid proteins are exclusively organised in pentamers. The approach, named `Viral Tiling Theory', is inspired by the theory of quasicrystals, where aperiodic Penrose tilings enjoy 5 ...
arxiv +1 more source
Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]
, 2019 Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid +7 more
core +1 more source
virusMED: an atlas of hotspots of viral proteins [PDF]
IUCrJ, 2021 Metal binding sites, antigen epitopes and drug binding sites are the hotspots in viral proteins that control how viruses interact with their hosts. virusMED (virus Metal binding sites, Epitopes and Drug binding sites) is a rich internet application based on a database of atomic interactions around hotspots in 7041 experimentally ...
Dejian Liu +11 more
openaire +4 more sources
ViralFP: A webserver of viral fusion proteins [PDF]
arXiv, 2021 Viral fusion proteins are attached to the membrane of enveloped viruses (a group that includes Coronaviruses, Dengue, HIV and Influenza) and catalyze fusion between the viral and host membranes, enabling the virus to insert its genetic material into the host cell.
arxiv
THE POSSIBLE COLLISIONS IN VIRUS INFECTION IMMUNODIAGNOSTICS AND VACCINATION
Инфекция и иммунитет, 2016 Antibodies (Ab), especially natural, display multiple specificity not only due to intrinsic conformational dynamics. With computational analysis the distribution of identical and homologous peptides has been studied in surface proteins from RNA and DNA ...
E. P. Kharchenko
doaj +1 more source
Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins [PDF]
Journal of Visualized Experiments, 2017 The goal of this protocol is to isolate herpes simplex virus type 1 (HSV-1) DNA from infected cells for the identification of associated viral and cellular proteins by mass spectrometry. Although proteins that interact with viral genomes play major roles in determining the outcome of infection, a comprehensive analysis of viral genome associated ...
Jill A. Dembowski, Neal A. DeLuca
openaire +3 more sources
Communication network model of the immune system identifies the impact of interactions with SARS-CoV-2 proteins [PDF]
arXiv, 2022 Interactions between SARS-CoV-2 and human proteins (SARS-CoV-2 PPIs) cause information transfer through biochemical pathways that contribute to the immunopathology of COVID-19. Here, we present a communication network model of the immune system to compute the information transferred by the viral proteins using the available SARS-CoV-2 PPIs data.
arxiv
HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread [PDF]
, 2016 open access articleHIV-1 spreads between CD4 T cells most efficiently through virus-induced cell-cell contacts. To test whether this process potentiates viral spread by activating signaling pathways, we developed an approach to analyze the ...
Jolly, Clare +3 more
core +2 more sources
Characterisation of a rare, reassortant human G10P[14] rotavirus strain detected in Honduras
Memorias do Instituto Oswaldo CruzBACKGROUND Although first detected in animals, the rare rotavirus strain G10P[14] has been sporadically detected in humans in Slovenia, Thailand, United Kingdom and Australia among other countries. Earlier studies suggest that the strains found in humans
Osbourne Quaye +8 more
doaj +1 more source
CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis
Viruses, 2011 Human immunodeficiency virus (HIV) infection is principally a mucosal disease and the gastrointestinal (GI) tract is the major site of HIV replication. Loss of CD4+ T cells and systemic immune hyperactivation are the hallmarks of HIV infection.
Angelita Rebollo +2 more
doaj +1 more source