Results 331 to 340 of about 2,261,873 (405)
Association Between Viral Replication Activity and Postoperative Recurrence of HBV-Related Hepatocellular Carcinoma. [PDF]
Heo S +17 more
europepmc +1 more source
Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong +19 more
wiley +1 more source
Host cellular protein RAB33B facilitates influenza viral replication and modulates M2 trafficking by enhancing autophagy. [PDF]
Ye S +11 more
europepmc +1 more source
NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang +8 more
wiley +1 more source
Duck plague virus gG is secreted, nonstructural glycoprotein, not essential for viral replication and responsible for the virulence. [PDF]
Qiu J +17 more
europepmc +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis. [PDF]
Sarkar L +5 more
europepmc +1 more source

