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Viral Genome Replication

2009
Genome replication strategies.- Model of Picornavirus RNA Replication.- Coronavirus Genome Replication.- Flaviviruses.- Hepatitis C Virus Genome Replication.- Brome Mosaic Virus RNA Replication and Transcription.- Retroviruses.- Hepadnaviral Genomic Replication.- Rhabdoviruses.- Orthomyxovirus Genome Transcription and Replication.- Arenaviruses: Genome
Kevin D Raney   +2 more
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Replication of the Viral RNA

1985
In the cytoplasm of an uninfected mammalian host cell, so far no enzymes have been detected that synthesize RNA on an RNA template. The incoming poliovirus contains a plus strand RNA but does not carry an RNA-replicase. Formation of replicase(s) is a prerequisite for the synthesis of viral progeny RNA.
Friedrich Koch, Gebhard Koch
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Initiation of Viral DNA Replication

1988
Publisher Summary This chapter focuses on the mechanisms involved in initiation of animal virus DNA replication. This step is of fundamental importance because it represents the central point of control of the replication process. Two of the best-characterized viruses, adenovirus and SV40, are discussed as examples of viruses that normally multiply ...
Joachim J. Li   +2 more
openaire   +3 more sources

MicroRNAs in Viral Replication and Pathogenesis

DNA and Cell Biology, 2007
MicroRNAs (miRNAs) are an important class of small, noncoding, regulatory RNAs found to be involved in regulating a wide variety of important cellular processes by the sequence-specific inhibition of gene expression. Viruses have evolved a number of mechanisms to take advantage of the regulatory potential of this highly conserved, ubiquitous pathway ...
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Strategy of Replication of the Viral Genome [PDF]

open access: possible, 1987
Unlike higher organisms, viruses utilize a wide range of strategies in the replication of their genome. This is clearly a consequence of their need to deal with genomes that may be single-stranded (ss), double-stranded (ds), or partially ds; with genomes that may be composed of DNA, RNA, or both (at different stages in their life cycle); and with ...
Milton W. Taylor, Howard V. Hershey
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Viral replication and the coactivators p300 and CBP

Trends in Microbiology, 2000
Productive viral infection requires coordinate regulation of viral and cellular gene expression. Viruses of different classes have evolved different mechanisms to conform to, adapt to and exploit programs of cellular gene expression. Many viral gene products influence and respond to cellular signals that control differentiation and proliferation ...
Gary J. Nabel, Michael O. Hottiger
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Replication of viral nucleic acids

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1970
Abstract 1. 1. Five different RNA components sedimenting at 45 S, 30–34 S, 22 S, 15 S and 3 S can be resolved by a glycerol-density gradient centrifugation for the Qβ RNA polymerase reaction in vitro. 2. 2. Both the 45-S and 34-S components were shown to be enzyme-RNA complexes, which are capable of synthesizing RNA only by the addition of ...
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Inhibition of viral replication by anticellular serum

Virology, 1963
Abstract The inhibition of ECHO and Coxsackie A9 viruses by antiserum to human amnion cells was investigated. The antiserum inhibited the intracellular replication of Coxsackie A9 virus in amnion cells but did not affect viral adsorption or eclipse.
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Viral Replication in Cell Cultures

1977
Adsorption of plaque-forming dengue-2 virus on KB cell monolayers follows essentially similar kinetics at 37° and at 28° C. At either temperature, the maximum number of PFU adsorbed is reached between 90 and 120 minutes after infection. However, it is reduced about 2-fold at the lower temperature (Schulze and Schlesinger, 1963a).
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