Results 211 to 220 of about 145,951 (305)

Platelets function as an acute viral reservoir during HIV-1 infection by harboring virus and T-cell complex formation. [PDF]

Blood Adv, 2020
Simpson SR, Singh MV, Dewhurst S, Schifitto G, Maggirwar SB.   +4 more
europepmc   +1 more source

Calcium signaling in plant defense

New Plant Protection, EarlyView.
Calcium signaling acts as a central hub in plant immunity, translating pathogen perception into defense responses. This review highlights the channels, sensors, and signaling networks involved, and discusses how pathogens subvert calcium dynamics, as well as how this knowledge may inspire innovative strategies for engineering durable crop resistance ...
Lifan Sun, Yu Wang, Jie Zhang
wiley   +1 more source

HIVconsv Vaccines and Romidepsin in Early-Treated HIV-1-Infected Individuals: Safety, Immunogenicity and Effect on the Viral Reservoir (Study BCN02). [PDF]

Front Immunol, 2020
Mothe B, Rosás-Umbert M, Coll P, Manzardo C, Puertas MC, Morón-López S, Llano A, Miranda C, Cedeño S, López M, Alarcón-Soto Y, Melis GG, Langohr K, Barriocanal AM, Toro J, Ruiz I, Rovira C, Carrillo A, Meulbroek M, Crook A, Wee EG, Miró JM, Clotet B, Valle M, Martinez-Picado J, Hanke T, Brander C, Moltó J, BCN02 Study Investigators.   +28 more
europepmc   +1 more source

Virus Ecology: Studying Animal Reservoirs to Understand Viral Emergence [PDF]

Drug Research, 2014
openaire   +2 more sources

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source

Correction: Immune response dynamics of SARS-CoV-2 vaccination in chronic lymphocytic leukemia individuals: a descriptive analysis

Frontiers in Immunology
Clara Sánchez-Menéndez, Clara Sánchez-Menéndez, Clara Sánchez-Menéndez, Alejandro Zurdo, Magdalena Corona, Elena Mateos de la Morenas, Elena Mateos de la Morenas, Sara Rodríguez-Mora, Sara Rodríguez-Mora, Guiomar Casado, Guiomar Casado, Javier García-Pérez, Javier García-Pérez, Mayte Pérez-Olmeda, Mayte Pérez-Olmeda, Susana Domínguez, María Aránzazu Murciano-Antón, Javier López-Jiménez, Valentín García-Gutiérrez, Mayte Coiras, Mayte Coiras, Montserrat Torres, Montserrat Torres   +22 more
doaj   +1 more source

The impact of COVID‐19 on public perceptions of wild meat in Central Africa

People and Nature, EarlyView.
Abstract Wild meat is a significant source of food and income generation in Central Africa. However, there is little knowledge of how the assumed link between COVID‐19 and wild meat consumption has been discussed by the media and received by the public. In this study, we conducted media content analysis of 264 articles published in 2019–2020 related to
Yuhan Li, Lude Kinzonzi, Paul Loundou, Divin Malekani, Krossy Mavakala, Christian Mikolo Yobo, Katharine Abernethy, Matilda Eve Dunn, Donald Midoko Iponga, Robert Mwinyihali, Joss Wright, Eleanor Jane Milner‐Gulland, Lauren Coad, Juliet H. Wright, Daniel W. S. Challender   +14 more
wiley   +1 more source

Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir. [PDF]

PLoS Pathog
Keele BF, Okoye AA, Fennessey CM, Varco-Merth B, Immonen TT, Kose E, Conchas A, Pinkevych M, Lipkey L, Newman L, Macairan A, Bosche M, Bosche WJ, Berkemeier B, Fast R, Hull M, Oswald K, Shoemaker R, Silipino L, Gorelick RJ, Duell D, Marenco A, Brantley W, Smedley J, Axthelm M, Davenport MP, Lifson JD, Picker LJ.   +27 more
europepmc   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source