Results 111 to 120 of about 337,413 (230)

Disruption of Transmembrane Phosphatidylserine Asymmetry by HIV-1 Incorporated SERINC5 Is Not Responsible for Virus Restriction

open access: yesBiomolecules
Host restriction factor SERINC5 (SER5) incorporates into the HIV-1 membrane and inhibits infectivity by a poorly understood mechanism. Recently, SER5 was found to exhibit scramblase-like activity leading to the externalization of phosphatidylserine (PS ...
Gokul Raghunath   +6 more
doaj   +1 more source

Delaying reverse transcription does not increase sensitivity of HIV-1 to human TRIM5α.

open access: yesPLoS ONE, 2013
BackgroundBecause uncoating of the capsid is linked to reverse transcription, modifications that delay this process lead to the persistence in the cytoplasm of capsids susceptible to recognition by the human restriction factor TRIM5α (hTRIM5α).
Emilie Battivelli   +3 more
doaj   +1 more source

Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication [PDF]

open access: green, 2021
Santseharay Ramírez   +15 more
openalex   +1 more source

Growth of Pseudotypes of Vesicular Stomatitis Virus with N-Tropic Murine Leukemia Virus Coats in Cells Resistant to N-Tropic Viruses [PDF]

open access: yes, 1973
Formation of pseudotypes between murine RNA tumor viruses and vesicular stomatitis virus (VSV) has been confirmed. Pseudotypes of VSV genomes coated by the surface envelope from an N-tropic tumor virus grew equally well in cells homozygous for either the
Baltimore, David   +3 more
core   +1 more source

Minimal hepatic toxicity of Onyx-015: spatial restriction of coxsackie-adenoviral receptor in normal liver. [PDF]

open access: yes, 2007
We administered an adenoviral vector, Onyx-015, into the hepatic artery of patients with metastatic colorectal cancer involving the liver. Thirty-five patients enrolled in this multi-institutional phase I/II trial received up to eight arterial infusions ...
Au, T   +5 more
core  

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members [PDF]

open access: bronze, 2010
Stéphane Daffis   +18 more
openalex   +1 more source

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