Results 141 to 150 of about 337,413 (230)

Screening for the optimal siRNA targeting a novel gene (HA117) and construction and evaluation of a derivative recombinant adenovirus [PDF]

, 2010
We found a novel gene named as HA117 in our previous research. At this study, we screened for an optimal siRNA targeting the novel gene HA117 using the pSOS-HUS method, verified the results of pSOS-HUS siRNA screening for optimal affinity for the target ...
Gaihuan Zheng, Qing Luo, Xianqing Jin, Youhua Xu, Yuxia Guo   +4 more
core   +1 more source

Restriction of Viral Replication, Rather than T Cell Immunopathology, Drives Lethality in Murine Norovirus CR6-Infected STAT1-Deficient Mice

, 2022
Andrew J Sharon, Heather A Filyk, Nicolette M. Fonseca, Rachel L. Simister, Renata B. Filler, Wallace Yuen, Blair K Hardman, Hannah G Robinson, Jung Hee Seo, Joana Rocha‐Pereira, Ian Welch, Johan Neyts, Craig B. Wilen, Sean A. Crowe, Lisa C. Osborne   +14 more
openalex   +2 more sources

Mucus Physically Restricts Influenza A Viral Particle Access to the Epithelium

Advanced Biology
AbstractPrior work suggests influenza A virus (IAV) crosses the airway mucus barrier in a sialic acid‐dependent manner through the actions of the viral envelope proteins, hemagglutinin, and neuraminidase. However, host and viral factors that influence how efficiently mucus traps IAV remain poorly defined.
Logan Kaler, Elizabeth M. Engle, Maria Corkran, Ethan Iverson, Allison Boboltz, Maxinne A. Ignacio, Taj Yeruva, Margaret A. Scull, Gregg A. Duncan   +8 more
openaire   +2 more sources

Calorie restriction partially attenuates sickness behavior induced by viral mimetic poly I:C

, 2023
Simone N. De Luca, L. Kivivali, Ken T. K. Chong, Alice Kirby, Adam J. Lawther, Jason Nguyen, Matthew W. Hale, Stephen Kent   +7 more
openalex   +1 more source

SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity. [PDF]

Autoimmunity, 2018
Mauney CH, Hollis T.
europepmc   +1 more source

231 The MHC Class II Transactivator, CIITA, is a Viral Restriction Factor for Human Oncogenic Retroviruses

, 2011
Giovanna Tosi, Greta Forlani, Vibeke Andresen, Marco Turci, Umberto Bertazzoni, Genoveffa Franchini, Roberto S. Accolla   +6 more
openalex   +1 more source

Stochastic modelling of the effects of human-mobility restriction and viral infection characteristics on the spread of COVID-19

, 2020
Shiho Ando, Yuki Matsuzawa, Hiromichi Tsurui, Testuya Mizutani, Damien Hall, Yutaka Kuroda   +5 more
openalex   +1 more source

Expression of HIV-1 Vpu Leads to Loss of the Viral Restriction Factor CD317/Tetherin from Lipid Rafts and Its Enhanced Lysosomal Degradation

, 2013
Ruth Rollason, Katie Dunstan, Peter G. Billcliff, Paul N. Bishop, Paul A. Gleeson, Helen Wise, Paul Digard, George Banting   +7 more
openalex   +2 more sources

Human primary macrophages derived in vitro from circulating monocytes comprise adherent and non-adherent subsets with differential expression of Siglec-1 and CD4 and permissiveness to HIV-1 infection [PDF]

, 2017
Abdel-Mohsen, Akridge, Barr, Bishop, Cai, Cai, Campbell, Chaipan, Colomer-Lluch, Crowe, Daugherty, Ellery, Fitzpatrick, Gartner, Gaudin, Germinario, Giese, Ginhoux, Goldstone, Gonzalez-Scarano, Gosselin, Hammonds, Hancock, Hashimoto, Hassan, Hatch, Hoeffel, Honeycutt, Igarashi, Izquierdo-Useros, Jambo, Jaworowski, Jenkins, Jobe, Jobe, Kajaste-Rudnitski, Kedzierska, Kim, Koppensteiner, Koppensteiner, Krisko, Kuroda, Laguette, Lahouassa, Law, Li, Liu, Mlcochova, Montaner, Orenstein, Pertel, Phipson, Pino, Puryear, Ritchie, Rom, Rosa, Santa-Marta, Schmidt, Schnell, Sieweke, Sonza, St Gelais, Stabell, Swaminathan, Swingler, Tan, Turrini, Usami, Van Damme, Wang, Yan, Zou   +72 more
core   +2 more sources

Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization. [PDF]

Nucleic Acids Res, 2017
Adolph MB, Ara A, Feng Y, Wittkopp CJ, Emerman M, Fraser JS, Chelico L.   +6 more
europepmc   +1 more source