Results 201 to 210 of about 337,413 (230)
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Daxx, a broad-spectrum viral restriction factor.
Virologie (Montrouge, France), 2016Daxx is an ubiquitous protein that was first identified as a Fas-interacting protein. Although cytoplasmic Daxx is involved in apoptosis, it is predominantly a nuclear protein. In the nucleus, Daxx is mainly located within PML nuclear bodies (PML NBs), nuclear structures involved in many cellular processes.
Sarah Maillet, Sébastien Nisole
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Restricted expression of viral glycoprotein in cells of persistently infected mice
Nature, 1982For a virus to cause persistent infection in a host, a unique host–virus relationship is required. The virus per se, or variant(s) arising in vivo, must be noncytopathic for the host cell that it infects. Furthermore, the infected cell must escape recognition by the host's immune system, which eliminates virus and virus-infected cells.
Oldstone, M B, Buchmeier, M J
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Structure of vaccinia DNA: Analysis of the viral genorne by restriction endonucleases
Virology, 1978DNA from the WR strain of vaccinia virus was cleaved with five restriction endonucleases and the molecular weight of each restriction fragment was determined. From a summation of the molecular weights of these DNA fragments, the molecular weight of the vaccinia genome was estimated to be approximately 130 × 106. By electrophoresis in agarose gels under
Mariano Esteban +4 more
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Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies
Medical Microbiology and Immunology, 2019SAMHD1 was initially described for its ability to efficiently restrict HIV-1 replication in myeloid cells and resting CD4+ T cells. However, a growing body of evidence suggests that SAMHD1-mediated restriction is by far not limited to lentiviruses, but seems to be a general concept that applies to most retroviruses and at least a number of DNA viruses.
Jan Moritz Schüssler +3 more
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HLA-restricted recognition of viral antigens in HLA transgenic mice
Nature, 1987Cytotoxic T lymphocytes (CTL) recognize antigen in the context of the class-I products of the major histocompatibility complex (MHC). The extensive polymorphism of class-I molecules is thought to be linked to their capacity to present a large variety of foreign antigens.
Femia Kievits +4 more
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Restricted expression of viral surface proteins in canine distemper encephalitis
Acta Neuropathologica, 1993Sixteen dogs with naturally occurring acute and chronic canine distemper virus (CDV) encephalitis were examined immunohistochemically for the presence of the five major CDV-specific proteins in the central nervous system. Monoclonal antibodies (mAbs) directed against two, three, four and five epitopes of the nucleo- (N), phospho- (P), fusion (F), and ...
C. Örvell +2 more
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Fetal growth restriction and viral infection
Prenatal Diagnosis, 2004Malgorzata A. Verboon-Maciolek +4 more
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Processing of viral antigens and presentation to class II-restricted T cells
Immunology Today, 1986Some antigens require intracellular processing by antigen presenting cells before being presented to T cells in conjunction with surface major histocompatibility complex antigens. The whole mechanism of these processing events is not known and in this article, Kingston Mills puts forward arguments for alternative routes of antigen processing, with ...
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Perinatal Viral Infections as a Cause of Intrauterine Growth Restriction
2000IUGR is a major cause of perinatal morbidity and mortality; indeed with increasing incidence of detection and “salvage” of the very low birthweight fetus such complications will continue to rise [1].
Mark Kilby, Sheena Hodgett
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