Advanced Functional Materials, EarlyView.This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao +9 more
wiley +1 more source
Ebola Virus Glycoprotein Promotes Enhanced Viral Egress by Preventing Ebola VP40 From Associating With the Host Restriction Factor BST2/Tetherin [PDF]
, 2015 Jean K. Gustin +3 more
openalex +1 more source
Engineering Hybrid Extracellular Vesicles for Functional mRNA Delivery
Advanced Functional Materials, EarlyView.This study optimizes two methods for the generation of extracellular vesicle (EV)‐mimetic‐Lipid Nanoparticle (LNP) (CELLNPs) and EV‐LNP (HEVs) hybrid nanoparticles for messenger (mRNA) delivery. The authors screen lipid compositions to maximize hybrid nanoparticle formation and analyze the resulting nanoparticles with single particle characterization ...
Ana Filipa Louro +6 more
wiley +1 more source
Short Communication: HIV-1 Infection Suppresses Circulating Viral Restriction microRNAs. [PDF]
AIDS Res Hum Retroviruses, 2016 Zhou Y +12 more
europepmc +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Advanced Functional Materials, EarlyView.Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Plant Virus Genome Is Shaped by Specific Dinucleotide Restrictions That Influence Viral Infection [PDF]
, 2020 Alfonso González de Prádena +5 more
openalex +1 more source
Advanced Functional Materials, EarlyView.The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong +7 more
wiley +1 more source
Nonsense-mediated decay serves as a general viral restriction mechanism in plants. [PDF]
Cell Host Microbe, 2014 Garcia D, Garcia S, Voinnet O.
europepmc +1 more source
Advanced Functional Materials, EarlyView.This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han +17 more
wiley +1 more source
Highly Multiplexed Proteomic Analysis of HCMV-Infected Dendritic Cells Reveals Global Manipulation of Adaptive Immunity and Host Restriction of Viral Replication [PDF]
Lauren Kerr-Jones +12 more
openalex +1 more source