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Host Cell Restriction Factors of Bunyaviruses and Viral Countermeasures [PDF]
Viruses, 2021 The Bunyavirales order comprises more than 500 viruses (generally defined as bunyaviruses) classified into 12 families. Some of these are highly pathogenic viruses infecting different hosts, including humans, mammals, reptiles, arthropods, birds, and/or plants.
Lerolle, Solène +3 more
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Viruses, 2023 Rift Valley Fever virus (RVFV) and Toscana virus (TOSV) are two pathogenic arthropod-borne viruses responsible for zoonotic infections in both humans and animals; as such, they represent a growing threat to public and veterinary health.
Marie-Pierre Confort +8 more
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Tethering Viral Restriction to Signal Transduction [PDF]
Cell Host & Microbe, 2014 Tetherin serves as an innate sensor of viral infection in addition to its role in inhibiting virus release from infected cells. In this issue, Galão et al. (2014) provide important insights into the mechanism of virus-induced signal transduction by tetherin.
Arias, Juan F., Evans, David T.
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West Nile Virus Restriction in Mosquito and Human Cells: A Virus under Confinement
Vaccines, 2020 West Nile virus (WNV) is an emerging neurotropic flavivirus that naturally circulates between mosquitoes and birds. However, WNV has a broad host range and can be transmitted from mosquitoes to several mammalian species, including humans, through ...
Marie-France Martin, Sébastien Nisole
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SARS-CoV-2 ORF7a potently inhibits the antiviral effect of the host factor SERINC5
Nature Communications, 2022 SERINC5, is a cellular multipass transmembrane protein involved in sphingolipid and phosphatydilserine biogenesis and a known retroviral restriction factor. Here, Timilsina et al.
Uddhav Timilsina +4 more
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Examination of the APOBEC3 Barrier to Cross Species Transmission of Primate Lentiviruses
Viruses, 2021 The transmission of viruses from animal hosts into humans have led to the emergence of several diseases. Usually these cross-species transmissions are blocked by host restriction factors, which are proteins that can block virus replication at a specific ...
Amit Gaba, Ben Flath, Linda Chelico
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Host-dependent restriction of mengovirus replication. II. Effect of host restriction on late viral RNA synthesis and viral maturation [PDF]
Journal of Virology, 1975 Restricted mengovirus replication in Mandin-Darby bovine kidney (MDBK) cells is characterized by a 400-fold reduction in infectious virus yield and a 40-fold increase in the production of noninfectious virus. Using conditions which insure that all MDBK cells are infected, virus-specific RNA and protein synthesis were measured in the restrictive host ...
S O, Prather, M W, Taylor
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mBio, 2023 Sterile α motif and HD domain-containing protein 1 (SAMHD1) is a dNTP triphosphate triphosphohydrolase (dNTPase) and a potent restriction factor for immunodeficiency virus 1 (HIV-1), active in myeloid and resting CD4+ T cells.
Moritz Schüssler +7 more
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Restricted Diffusion of the Splenium of the Corpus Callosum in Viral Meningitis [PDF]
The Neurohospitalist, 2013 Infarcts of the corpus callosum are rare. This may be due to the rich blood supply of the corpus callosum which includes the anterior and posterior cerebral arteries and the anterior communicating arteries.1 Sometimes, imaging findings suggestive of acute stroke can in fact be related to nonprimary stroke radiologic mimics such as an infectious process.
Mark, Oquist +2 more
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Sequence organization of feline leukemis virus DNA in infected cells [PDF]
, 1980 A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W. +3 more
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