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Host Cell Virus Interactions: Molecular Mechanisms, Immune Modulation, Viral Pathogenesis, and Emerging Therapeutic Targets. [PDF]

Viruses
Alanazi A, Ibrahim MN, El Azab EF, Elithy MA.   +3 more
europepmc   +1 more source

Mammalian antiviral proteins ZAP and KHNYN can independently restrict CpG-enriched avian viruses. [PDF]

PLoS Biol
Becker JT, Mickelson CK, Pross LM, Sanders AE, Vogt ER, Shepherd FK, Wick C, Barkhymer AJ, Aron SL, Fay EJ, Harris RS, Langlois RA.   +11 more
europepmc   +1 more source

Construction and Immunogenicity Evaluation of a Recombinant Infectious Bronchitis Virus H120-Based Vaccine in Broiler Chickens. [PDF]

Animals (Basel)
Nayef A, Jibreen S, Ababneh M.
europepmc   +1 more source

Construction of a Full-Length Infectious Clone Derived from Type O Foot-and-Mouth Disease Virus Isolated in South Korea for Vaccine Development with High Antigen Productivity. [PDF]

Vaccines (Basel)
Kim JY, Park SY, Lee G, Park SH, Jin JS, Park JH, Ko YJ.   +6 more
europepmc   +1 more source

Mass Spectrometry-Based Proteomic Analysis of Porcine Reproductive and Respiratory Syndrome Virus NSP9 Protein with Host Proteins. [PDF]

Animals (Basel)
Wen W, Liu Y, Wang W, Zhu Z, Li X.
europepmc   +1 more source

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The Upf1 protein restricts EV-A71 viral replication

Microbes and Infection, 2023
Enterovirus A71 (EV-A71) is transmitted through the respiratory tract, gastrointestinal system, and fecal-oral routes. The main symptoms caused by EV-A71 are hand, foot, and mouth disease (HFMD) or vesicular sore throat. Upf1 (Up-frameshift protein 1) was reported to degrade mRNA containing early stop codons, known as nonsense-mediated decay (NMD ...
Peng Xu, Wei Tong, Chen-Yen Kuo, Han-Hsiang Chen, Robert Y.L. Wang   +4 more
openaire   +2 more sources

APOBEC-mediated viral restriction: not simply editing?

Trends in Biochemical Sciences, 2007
The APOBEC family of cytidine deaminases inhibit the mobility of diverse retroviruses, retrotransposons and other viruses. Initial reports proposed that these effects were due to the DNA editing capabilities of these enzymes; however, many recent studies have provided evidence suggesting that APOBEC proteins can inhibit these elements by several ...
Holmes, RK, Malim, MH, Bishop, KN
openaire   +3 more sources

Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies

Medical Microbiology and Immunology, 2019
SAMHD1 was initially described for its ability to efficiently restrict HIV-1 replication in myeloid cells and resting CD4+ T cells. However, a growing body of evidence suggests that SAMHD1-mediated restriction is by far not limited to lentiviruses, but seems to be a general concept that applies to most retroviruses and at least a number of DNA viruses.
Catharina Majer, Jan Moritz Schüssler, Renate König   +2 more
openaire   +2 more sources