Results 61 to 70 of about 363,177 (305)

LUJO HEMORRHAGIC FEVER

Вопросы вирусологии, 2017
Lujo hemorrhagic fever (LHF) is a viral disease accompanied with fever, headache, vomiting, diarrhea, arthralgia, myalgia and numerous signs of hemorrhagic syndrome. LHF causes a clinical syndrome remarkably similar to Lassa hemorrhagic fever.
T. E. Sizikova, V. N. Lebedev, S. I. Syromyatnikova, S. V. Borisevich   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Towards a Universal Translator: Decoding the PTMs That Regulate Orthoflavivirus Infection

Viruses
Post-translational modifications (PTMs) serve as critical regulators of protein function across biological systems, including during viral infection. For orthoflaviviruses, including human pathogens like dengue, Zika, and West Nile viruses, PTMs on viral
Hannah M. Schmidt, Stacy M. Horner
doaj   +1 more source

Recognition of mRNA cap structures by viral and cellular proteins

Journal of General Virology, 2005
Most cellular and eukaryotic viral mRNAs have a cap structure at their 5′ end that is critical for efficient translation. Cap structures also aid in mRNA transport from nucleus to cytoplasm and, in addition, protect the mRNAs from degradation by 5′ exonucleases.
Pierre, Fechter, George G, Brownlee
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The human interferon-induced MxA protein inhibits early stages of influenza A virus infection by retaining the incoming viral genome in the cytoplasm [PDF]

, 2013
The induction of an interferon-induced antiviral state is a powerful cellular response against viral infection that limits viral spread. Here we show that a pre-existing antiviral state inhibits replication of influenza A viruses in human A549 cells by ...
Xiao, Han, Killip, Marian Jane, Killip, Marian J., Stäheli, Peter, Staeheli, Peter, Randall, Richard Edward, Jackson, David   +6 more
core   +1 more source

Spatiotemporal Coupling of the Hepatitis C Virus Replication Cycle by Creating a Lipid Droplet- Proximal Membranous Replication Compartment

Cell Reports, 2019
Summary: The hepatitis C virus (HCV) is a major cause of chronic liver disease, affecting around 71 million people worldwide. Viral RNA replication occurs in a membranous compartment composed of double-membrane vesicles (DMVs), whereas virus particles ...
Ji-Young Lee, Mirko Cortese, Uta Haselmann, Keisuke Tabata, Inés Romero-Brey, Charlotta Funaya, Nicole L. Schieber, Yu Qiang, Marie Bartenschlager, Stephanie Kallis, Christian Ritter, Karl Rohr, Yannick Schwab, Alessia Ruggieri, Ralf Bartenschlager   +14 more
doaj   +1 more source

Structures of viral membrane proteins by high-resolution cryoEM [PDF]

Current Opinion in Virology, 2014
Cryo electron microscopy (cryoEM) has emerged as an excellent tool for resolving high-resolution three-dimensional structures of membrane proteins in a lipid-containing environment with interacting partners. The near atomic resolution structures of Venezuelan equine encephalitis virus and dengue virus revealed transmembrane helices in lipid bilayers ...
openaire   +4 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Coalescence of the sites of cowpea mosaic virus RNA replication into a cytopathic structure [PDF]

, 2002
Cowpea mosaic virus (CPMV) replication induces an extensive proliferation of endoplasmic reticulum (ER) membranes, leading to the formation of small membranous vesicles where viral RNA replication takes place.
Carette, J.E., Gühl, K., Wellink, J., Kammen, A., van   +3 more
core   +1 more source