Results 11 to 20 of about 2,929 (132)
Harvesting AAV by tangential flow filtration using reverse asymmetric membranes. [PDF]
Biotechnol ProgAbstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Hao X +5 more
europepmc +2 more sources
Minimizing batch-to-batch variability of a live virus vaccine by process analytical technologies. [PDF]
Biotechnol ProgAbstract For bioprocesses producing live virus, such as enterovirus Coxsackievirus A21, viral titer (infectivity basis) decay rates can exceed 30% within a day. Consequently, harvest timing is paramount. To optimize titer at harvest, a continuous viral product titer model was generated to elucidate kinetics.
Forrester K +4 more
europepmc +2 more sources
Construction and characterization of H5N1-recombinant fowlpox viruses co-expressing host cytokines [PDF]
, 2011 Possessing a large double stranded DNA genome up to 300 kb, fowlpox virus (FWPV) has been developed to express avian influenza virus (AIV) antigens since the late 1980s. A more advanced approach would be to coexpress host cytokines from such recombinants.
Abdul Razak, Mariatulqabtiah +1 more
core +1 more source
Genetically modified bacteriophages [PDF]
, 2016 Phages or bacteriophages, viruses that infect and replicate inside bacteria, are the most abundant microorganisms on earth. The realization that antibiotic resistance poses a substantial risk to the world’s health and global economy is revitalizing phage
Grigonyte, Aurelija M. +3 more
core +1 more source
pDNA capture using grafted adsorbents [PDF]
, 2018 BACKGROUND: ‘Expanded’ composite materials are of interest as an alternative, or as a supplement, to packed-bed chromatography during bioproduct recovery and purification.
Bencina +24 more
core +1 more source
Optimizing sterile filtration of nanoemulsions through proper choice of prefilter properties
Biotechnology Progress, EarlyView.Abstract Nanoemulsions, with droplet sizes between 20 and 200 nm, have emerged as a promising vaccine adjuvant and drug delivery system, enhancing the solubility of hydrophobic drugs for diverse applications. Sterile filtration of nanoemulsions is particularly challenging due to the similar size between the nanodroplets and the 0.2 μm nominal pore size
Shreya Kapila +4 more
wiley +1 more source
, 2019 Influenza A virus (IAV) infection poses a serious health threat and novel antiviral strategies are needed. Defective interfering particles (DIPs) can be generated in IAV infected cells due to errors of the viral polymerase and may suppress spread of wild
Arora, P. +6 more
core +2 more sources
Bactericidal properties of plants-derived metal and metal oxide nanoparticles (NPs) [PDF]
, 2018 Nanoparticles (NPs) are nano-sized particles (generally 1–100 nm) that can be synthesized through various methods. The wide range of physicochemical characteristics of NPs permit them to have diverse biological functions.
Peh, Suat Cheng * +4 more
core +2 more sources
The Canadian Journal of Chemical Engineering, EarlyView.Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía +3 more
wiley +1 more source
Tomato (Solanum lycopersicum L.) in the service of biotechnology [PDF]
, 2014 Originating in the Andes, the tomato (Solanum lycopersicum L.) was imported to Europe in the 16th century. At present, it is an important crop plant cultivated all over the world, and its production and consumption continue to increase.
Gerszberg, Aneta +3 more
core +2 more sources