Results 21 to 30 of about 853,787 (154)

The Potential of Influenza HA-Specific Immunity in Mitigating Lethality of Postinfluenza Pneumococcal Infections

open access: yesVaccines, 2019
: Influenza virus infections pre-dispose an individual to secondary pneumococcal infections, which represent a serious public health concern. Matching influenza vaccination was demonstrated helpful in preventing postinfluenza bacterial infections and ...
Miriam Klausberger   +10 more
doaj   +1 more source

Bovine Neonatal Pancytopenia-Associated Alloantibodies Recognize Individual Bovine Leukocyte Antigen 1 Alleles

open access: yesFrontiers in Immunology, 2018
Bovine neonatal pancytopenia (BNP) was a vaccine-induced alloimmune disease observed in young calves and characterized by hemorrhages, pancytopenia, and severe destruction of the hematopoietic tissues.
Rahel Kasonta   +8 more
doaj   +1 more source

Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference. [PDF]

open access: yes, 2010
EUROPRISE is a Network of Excellence sponsored from 2007 to 2011 by the European Commission within the 6th Framework Program. The Network encompasses a wide portfolio of activities ranging from an integrated research program in the field of HIV vaccines ...
Palma, Paolo   +119 more
core   +2 more sources

Evidence of blood stage efficacy with a virosomal malaria vaccine in a Phase IIa clinical trial [PDF]

open access: yes, 2008
Background Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine.
Zurbriggen, R   +75 more
core   +1 more source

Preferential amplification of CD8 effector-T cells after transcutaneous application of an inactivated influenza vaccine: a randomized phase I trial [PDF]

open access: yes, 2010
Background: Current conventional vaccination approaches do not induce potent CD8 T-cell responses for fighting mostly variable viral diseases such as influenza, avian influenza viruses or HIV.
van der Werf, Sylvie   +26 more
core   +2 more sources

Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis

open access: yesAngewandte Chemie, Volume 138, Issue 39, 21 September 2026.
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood   +6 more
wiley   +2 more sources

Selective expansion of viral variants following experimental transmission of a reconstituted feline immunodeficiency virus quasispecies [PDF]

open access: yes, 2013
Following long-term infection with virus derived from the pathogenic GL8 molecular clone of feline immunodeficiency virus (FIV), a range of viral variants emerged with distinct modes of interaction with the viral receptors CD134 and CXCR4, and ...
Margaret J Hosie   +23 more
core   +1 more source

Enhanced production yields of rVSV-SARS-CoV-2 vaccine using Fibra-Cel® macrocarriers

open access: yesFrontiers in Bioengineering and Biotechnology
The COVID-19 pandemic has led to high global demand for vaccines to safeguard public health. To that end, our institute has developed a recombinant viral vector vaccine utilizing a modified vesicular stomatitis virus (VSV) construct, wherein the G ...
Noam Cohen   +36 more
doaj   +1 more source

A DNA vaccine construct incorporating intercellular trafficking and intracellular targeting motifs effectively primes and induces memory B and T cell responses in outbred animals [PDF]

open access: yes, 2007
We developed a vaccine construct in which a BVP22 domain and an invariant-chain major histocompatibility complex class II-targeting motif capable of enhancing dendritic cell antigen uptake and presentation were fused to a sequence encoding a B- and T ...
Palmer, Guy H   +19 more
core   +1 more source

Molecular and process design for rotavirus-like particle production in Saccharomyces cerevisiae

open access: yesMicrobial Cell Factories, 2011
Background Virus-like particles (VLP) have an increasing range of applications including vaccination, drug delivery, diagnostics, gene therapy and nanotechnology.
Palomares Laura A   +4 more
doaj   +1 more source

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